Results 131 to 140 of about 7,457 (263)
Magnesium isotopes as a probe of the Milky Way chemical evolution
, 2015 The study of elemental abundance ratios from spectroscopy of stars has for a long time been used to investigate the structure and the chemical evolution history of the Milky Way.
Thygesen, Anders Overaa
core +1 more source
Advanced Science, EarlyView.Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang +13 more
wiley +1 more source
Advanced Science, EarlyView.Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu +12 more
wiley +1 more source
Chemical Elements as Tracers of the Evolution of the Milky Way
To better understand the processes that have formed the Milky Way and enriched the galactic gas, we can study galactic chemical evolution (GCE). When we study GCE we combine our understanding of galaxy formation with stellar evolution to trace the ...
Womack, Kate
core +1 more source
Efficient and Accurate Force Replay in Cosmological-baryonic Simulations
The Astrophysical JournalWe construct time-evolving gravitational potential models for a Milky Way–mass galaxy from the FIRE-2 suite of cosmological-baryonic simulations using basis function expansions.
Arpit Arora +10 more
doaj +1 more source
Advanced Science, EarlyView.Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia +17 more
wiley +1 more source
Advanced Science, EarlyView.By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao +11 more
wiley +1 more source
The APO-K2 Catalog. II. Accurate Stellar Ages for Red Giant Branch Stars across the Milky Way
The Astronomical JournalWe present stellar age determinations for 4661 red giant branch stars in the APO-K2 catalog, derived using mass estimates from K2 asteroseismology from the K2 Galactic Archaeology Program and elemental abundances from the Apache Point Galactic Evolution ...
Jack T. Warfield +13 more
doaj +1 more source
Advanced Science, EarlyView.This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang +16 more
wiley +1 more source
The Astrophysical JournalThis study probes the chemical abundances of the neutron-capture elements cerium and neodymium in the inner Milky Way from an analysis of a sample of ∼2000 stars in the Galactic bulge bar spatially contained within ∣ X _Gal ∣ < 5 kpc, ∣ Y _Gal ∣ < 3.5 ...
J. V. Sales-Silva +30 more
doaj +1 more source