Results 111 to 120 of about 7,457 (263)

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino   +12 more
wiley   +1 more source

Where is the Supervirial Gas? The Supply from Hot Inflows

open access: yesThe Astrophysical Journal
To understand the presence of the supervirial temperature gas detected in the Milky Way (MW), we present our findings from isolated galaxy simulations of MW-mass systems using GIZMO with the Feedback in Realistic Environments (FIRE-2) stellar feedback ...
Manami Roy   +3 more
doaj   +1 more source

Gellan Gum Fluid Gel System for Controlled‐Delivery of Cytokine‐Licensed MSC‐EVs to Enhance Corneal Repair in Limbal Stem Cell Deficiency

open access: yesAdvanced Healthcare Materials, EarlyView.
Gellan gum fluid gel (FG) enables controlled ocular delivery of mesenchymal stromal cell (MSC)‐derived extracellular vesicles (EV). Its shear‐thinning, solid‐liquid‐solid rheology ensures prolonged ocular retention. Sustained MSC‐EV release (∼18% in 6 hrs) supports effective EV ocular delivery.
Seyedmohammad Moosavizadeh   +7 more
wiley   +1 more source

Differential Accretion of Ionized Low-velocity Gas at the Milky Way’s Disk–Halo Interface

open access: yesThe Astrophysical Journal
We measure line-of-sight velocities of metal absorption and H I emission along 132 QSO sight lines in order to study gas accretion and outflow at the disk–halo interface of the Milky Way.
Hannah V. Bish   +5 more
doaj   +1 more source

Thermally Modulated Metasurface Sensor for Dynamic and Time‐Resolved Isolation of Extracellular Vesicles

open access: yesAdvanced Materials, EarlyView.
A thermally adaptive plasmonic metasurface, functionalized with poly(N‐isopropylacrylamide) (PNIPAM) and anti‐CD63 antibodies, enables precise, on‐demand capture and release of extracellular vesicles (EVs). Delivering high recovery, improved purity, and intact vesicle structure, the platform offers a versatile, label‐free solution for real‐time EV ...
Beyza Nur Kucuk   +7 more
wiley   +1 more source

The Milky Way Radial Metallicity Gradient as an Equilibrium Phenomenon: Why Old Stars Are Metal Rich

open access: yesThe Astrophysical Journal
Metallicities of both gas and stars decline toward large radii in spiral galaxies, a trend known as the radial metallicity gradient. We quantify the evolution of the metallicity gradient in the Milky Way as traced by APOGEE red giants with age estimates ...
James W. Johnson   +13 more
doaj   +1 more source

Evolution of the Milky Way Halo by Accretion of Dwarf Satellite Galaxies

open access: yes, 2011
Within the Cold Dark Matter scenario the hierarchical merging paradigm is the natural result to form massive galactic halos by the minor mergers of sub-halos and, by this, inherently their stellar halo.
G. Hensler, M. Petrov
core   +1 more source

Super‐Resolution Ultrasound Based Cell Tracking With Polymeric Nanobubbles

open access: yesAdvanced Materials, EarlyView.
This study presents a super‐resolution ultrasound platform for tracking cells in vivo. Biocompatible polymeric nanobubbles are used as highly echogenic intracellular labels. Following the injection of cells and microbubbles, ultrasound localization microscopy (ULM) can dynamically match the microvascular architecture and individual cell trajectories ...
Junlin Chen   +19 more
wiley   +1 more source

True Pair-instability Supernova Descendant: Implications for the First Stars’ Mass Distribution

open access: yesThe Astrophysical Journal Letters
The initial mass function (IMF) of the first Population III (Pop III) stars remains a persistent mystery. Their predicted massive nature implies the existence of stars exploding as pair-instability supernovae (PISNe), but no observational evidence had ...
Ioanna Koutsouridou   +2 more
doaj   +1 more source

Globular Clusters and the Milky Way Connected by Chemistry [PDF]

open access: yes, 2016
There are two ways to study galaxy formation and evolution: one is to observe a large number of galaxies at a variety of redshifts, the other is to observe in detail just a few nearby galaxies.
Ortolani, S.   +6 more
core  

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