Results 111 to 120 of about 247,055 (324)

A Component of the Smith High-velocity Cloud Now Crossing the Galactic Plane

open access: yesThe Astrophysical Journal, 2023
We have identified a new structure in the Milky Way: a leading component of the Smith high-velocity cloud that is now crossing the Galactic plane near longitude 25°. Using new 21 cm H i data from the Green Bank Telescope (GBT), we measured the properties
Felix J. Lockman   +3 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Why is the Milky Way X-factor Constant? [PDF]

open access: yes, 2013
The CO-H2 conversion factor (Xco; otherwise known as the X-factor) is observed to be remarkably constant in the Milky Way and in the Local Group (aside from the SMC). To date, our understanding of why Xco should be so constant remains poor.
Hopkins, Philip, Narayanan, Desika
core   +2 more sources

A 3D Chemodynamical Census of Inner-Galaxy Metal-poor Giants to [Fe/H] ∼ −3.5

open access: yesThe Astrophysical Journal Letters
The earliest assembly of the Milky Way remains poorly understood, yet the spatial, chemical, and kinematic properties of its most metal-poor stars provide a unique fossil record of its proto-Galaxy phase.
Shenglan Sun   +10 more
doaj   +1 more source

The Chemical Evolution of the Milky Way: the Three Infall Model

open access: yes, 2013
We present a new chemical evolution model for the Galaxy that assumes three main infall episodes of primordial gas for the formation of halo, thick and thin disk, respectively.
Matteucci, F., Micali, A., Romano, D.
core   +1 more source

A confirmed location in the Galactic halo for the high-velocity cloud 'chain A' [PDF]

open access: yes, 1999
The high-velocity clouds of atomic hydrogen, discovered about 35 years ago, have velocities inconsistent with simple Galactic rotation models that generally fit the stars and gas in the Milky Way disk.
Kalberla, Peter M. W.   +4 more
core   +4 more sources

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

The Extremely Metal-rich Knot of Stars at the Heart of the Galaxy

open access: yesThe Astrophysical Journal
We show with Gaia XP spectroscopy that extremely metal-rich (EMR) stars in the Milky Way ([M/H] _XP ≳ 0.5) are largely confined to a tight “knot” at the center of the Galaxy. This EMR knot is round in projection, has a fairly abrupt edge near R _GC,proj ∼
Hans-Walter Rix   +17 more
doaj   +1 more source

The Milky Way Bulge: Observed properties and a comparison to external galaxies

open access: yes, 2015
The Milky Way bulge offers a unique opportunity to investigate in detail the role that different processes such as dynamical instabilities, hierarchical merging, and dissipational collapse may have played in the history of the Galaxy formation and ...
A. Alves-Brito   +150 more
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

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