Results 91 to 100 of about 7,795,018 (296)

Milky Way versus Andromeda: a tale of two disks

open access: yes, 2009
Aims. We study the chemical evolution of the disks of the Milky Way (MW) and of Andromeda (M31), to identify the common properties and differences between the two major galaxies of the Local ...
J. L. Hou   +13 more
core   +1 more source

What Is Missing from the Local Stellar Halo?

open access: yesThe Astrophysical Journal
The Milky Way’s stellar halo, which extends to >100 kpc, encodes the evolutionary history of our Galaxy. However, most studies of the halo to date have been limited to within a few kiloparsecs of the Sun.
Katherine Sharpe   +2 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Watching Our Galaxy Grow Up: The Mass and Color Evolution of the Milky Way

open access: yesThe Astrophysical Journal
Using our rich observations within the Milky Way to better understand galaxy evolution requires understanding what the Milky Way looks like “as a galaxy”—that is, its “true” shape and abundance profiles (unskewed by observational biases), signatures of ...
Gail Zasowski   +2 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

The Dynamical Evolution of Accreted Star Clusters in the Milky Way [PDF]

open access: yes, 2016
We perform N-body simulations of star clusters in time-dependant galactic potentials. Since the Milky Way was built up through mergers with dwarf galaxies, its globular cluster population is made up of clusters formed both during the initial collapse of ...
Miholics, Meghan
core   +1 more source

The Stellar Disk Structure Revealed by the Mono-age Populations of the LAMOST Red Clump Star Sample

open access: yesThe Astronomical Journal
Understanding the structure of the Galactic disk is crucial for understanding the formation and evolutionary history of the Milky Way. This study examines the structure of the Galactic disk by analyzing a sample of 138,667 primary red clump (RC) stars ...
Zheng Yu   +4 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Chemical Elements as Tracers of the Evolution of the Milky Way [PDF]

open access: yes
To better understand the processes that have formed the Milky Way and enriched the galactic gas, we can study galactic chemical evolution (GCE). When we study GCE we combine our understanding of galaxy formation with stellar evolution to trace the ...
Womack, Kate
core   +6 more sources

Mapping the Chemodynamics of the Galactic Disk Using the LAMOST and APOGEE Red Clump Stars

open access: yesThe Astrophysical Journal Supplement Series
A detailed measurement is made of the metallicity distributions, kinematics, and dynamics of the thin and thick disks across a large disk volume (5.0 ≤ R ≤ 15.0 kpc and ∣ Z ∣ ≤ 3.0 kpc) by using the LAMOST–APOGEE red clump stars.
Weixiang Sun   +3 more
doaj   +1 more source

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