Results 91 to 100 of about 247,055 (324)

The Age-dependent Vertical Actions of Young Stars in the Galaxy

The Astrophysical Journal
Stars in the Galactic disk are born on cold, nearly circular orbits with small vertical excursions. After their birth, their orbits evolve, driven by small- or large-scale perturbations in the Galactic disk’s gravitational potential.
D. N. Garzon, Neige Frankel, Eleonora Zari, Maosheng Xiang, Hans-Walter Rix   +4 more
doaj   +1 more source

The AMBRE project: chemical evolution models for the Milky Way thick and thin discs [PDF]

, 2017
We study the chemical evolution of the thick and thin discs of the Galaxy by comparing detailed chemical evolution models with recent data from the AMBRE Project.
V. Grisoni, E. Spitoni, F. Matteucci, F. Matteucci, A. Recio-Blanco, P. Laverny, M. Hayden, Š. Mikolaitis, Š. Mikolaitis, C. Worley   +9 more
semanticscholar   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

The Milky Way’s Circular Velocity Curve Measured Using Element Abundance Gradients

The Astrophysical Journal
Spectroscopic surveys now supply precise stellar label measurements such as element abundances for large samples of stars throughout the Milky Way. These element abundances are known to correlate with orbital actions or other dynamical invariants.
Danny Horta, Adrian M. Price-Whelan, Sergey E. Koposov, Jason A. S. Hunt, David W. Hogg, Carrie Filion, Kathryn J. Daniel   +6 more
doaj   +1 more source

Detection of a Supervirial Hot Component in the Milky Way Circumgalactic Medium Along Multiple Sight Lines by Using the Stacking Technique

The Astrophysical Journal, 2023
The study of the elusive hot component ( T ≳ 10 ^7 K) of the Milky Way circumgalactic medium (CGM) is a novel topic for understanding Galactic formation and evolution.
Armando Lara-DI, Smita Mathur, Yair Krongold, Sanskriti Das, Anjali Gupta   +4 more
doaj   +1 more source

Red giants observed by CoRoT and APOGEE: The evolution of the Milky Way's radial metallicity gradient [PDF]

, 2016
Using combined asteroseismic and spectroscopic observations of 418 red-giant stars close to the Galactic disc plane (6 kpc $
F. Anders, C. Chiappini, I. Minchev, A. Miglio, J. Montalbán, B. Mosser, T. S. Rodrigues, T. S. Rodrigues, B. Santiago, F. Baudin, T. Beers, L. Costa, R. García, D. A. García-Hernández, D. A. García-Hernández, J. Holtzman, M. Maia, S. Majewski, S. Mathur, Arlette Noels-Grötsch, K. Pan, K. Pan, D. Schneider, M. Schultheis, M. Steinmetz, M. Valentini, O. Zamora, O. Zamora   +27 more
semanticscholar   +1 more source

Structure and Evolution of the Milky Way [PDF]

, 2011
Proc. of the workshop "Red Giants as Probes of the Structure and Evolution of the Milky Way" (Roma, 15-17 Nov 2010), Astrophysics and Space Science Proceedings, ISBN 978-3-642-18417-8 (eds. A. Miglio, J. Montalban, A. Noels).
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Estimating the Initial Mass of the Gaia–Enceladus Dwarf Galaxy with a Chemical Evolution Model

The Astrophysical Journal
This work investigates the initial mass and chemical evolution history of the Gaia–Enceladus dwarf galaxy. We combine spectroscopic data from APOGEE with astrometric data from Gaia Data Release 3 to identify Gaia–Enceladus candidate stars via a machine ...
Olcay Plevne, Furkan Akbaba
doaj   +1 more source

Figure Rotation of IllustrisTNG Halos

The Astrophysical Journal, 2023
We use the TNG50 and TNG50 dark matter (DM)-only simulations from the IllustrisTNG simulation suite to conduct an updated survey of halo figure rotation in the presence of baryons.
Neil Ash, Monica Valluri
doaj   +1 more source