Results 81 to 90 of about 7,457 (263)

Four-hundred Very Metal-poor Stars Studied with LAMOST and Subaru. III. Dynamically Tagged Groups and Chemodynamical Properties

open access: yesThe Astrophysical Journal
Very metal-poor (VMP) stars record the signatures of early accreted galaxies, making them essential tools for unraveling the early stages of Galaxy formation.
Ruizhi Zhang   +11 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Finding The Milky Way In 2mass

open access: yes, 2004
Article was published at http://www.aspbooks.org/a/volumes/article_details/?paper_id=1102133 ...
Weinberg, MD
core  

Radial migration and chemical evolution in the Milky Way

open access: yes, 2016
International audienceThe role of radial migration on the chemical evolution of the Milky Way is studied with semi-analytical models of disk evolution, using several new/updated ingredients and parametrized prescriptions for blurring and churning.
N. Prantzos, Prantzos, N.
core   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

The Rapid Formation of the Metal-poor Milky Way

open access: yesThe Astrophysical Journal
Our understanding of the assembly timeline of the Milky Way has been transforming along with the dramatic increase in astrometric and spectroscopic data available over the past several years.
Turner Woody   +8 more
doaj   +1 more source

The collision between the Milky Way and Andromeda and the fate of their supermassive black holes

open access: yes, 2019
Our Galaxy and the nearby Andromeda Galaxy (M31) form a bound system, even though the relative velocity vector of M31 is currently not well constrained.
Arca Sedda, Manuel   +7 more
core   +1 more source

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li   +11 more
wiley   +1 more source

Resolved Mass Assembly and Star Formation in Milky Way Progenitors since z = 5 from JWST/CANUCS: From Clumps and Mergers to Well-ordered Disks

open access: yesThe Astrophysical Journal
We present a resolved study of 877 progenitors of Milky Way Analogs (MWAs) at 0.3 
Vivian Yun Yan Tan   +19 more
doaj   +1 more source

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