Results 71 to 80 of about 247,055 (324)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Candidate Members of the VMP/EMP Disk System of the Galaxy from the SkyMapper and SAGES Surveys

open access: yesThe Astrophysical Journal Supplement Series
Photometric stellar surveys now cover a large fraction of the sky, probe to fainter magnitudes than large-scale spectroscopic surveys, and are relatively free from the target selection biases often associated with such studies.
Jihye Hong   +17 more
doaj   +1 more source

The Formalism of Milky-Way Antimatter-Domains Evolution

open access: yesGalaxies, 2023
If baryosynthesis is strongly nonhomogeneous, macroscopic regions with antibaryon excess can be created in the same process from which the baryonic matter is originated. This exotic possibility can become real, if the hints to the existence of antihelium
Maxim Yu. Khlopov, Orchidea Maria Lecian
doaj   +1 more source

The evolution of the Sun's birth cluster and the search for the solar siblings with Gaia [PDF]

open access: yes, 2016
We use self-consistent numerical simulations of the evolution and disruption of the Sun's birth cluster in the Milky Way potential to investigate the present-day phase space distribution of the Sun's siblings.
Antiche, E.   +5 more
core   +3 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Observational Constraints of Radial Migration in the Galactic Disk Driven by the Slowing Bar

open access: yesThe Astrophysical Journal Letters
Radial migration is an important dynamical effect that has reshaped the Galactic disk, but its origin has yet to be elucidated. In this work, we present evidence that resonant dragging by the corotation of a decelerating bar could be the main driver of ...
HanYuan Zhang   +9 more
doaj   +1 more source

The effect of stellar migration on Galactic chemical evolution: a heuristic approach [PDF]

open access: yes, 2015
In the last years, stellar migration in galactic discs has been the subject of several investigations. However, its impact on the chemical evolution of the Milky Way still needs to be fully quantified.
Ciotti, L.   +3 more
core   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Distributions and collision rates of ALP stars in the Milky Way [PDF]

open access: yesPhysical Review D
We apply current analytical knowledge on the characteristic mass and linear evolution of miniclusters down to redshift $z=0$ to the hypothetical minicluster distribution of the Milky Way. Using the mass-radius relation and a core-halo relation for stable
Dennis Maseizik, G. Sigl
semanticscholar   +1 more source

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