Results 161 to 170 of about 76,255 (323)

Bi‐Functional Topospecific Nanoparticles to Promote Immune‐Tumor Cell Engagement as A New Immunotherapeutic Strategy

Advanced Materials, EarlyView.
A Janus‐engineered nanoplatform (J‐pHLIP‐PD1), featuring separate tumor‐ and immune‐targeting faces, bridges melanoma cells and cytotoxic T lymphocytes using toposelective pHLIP and anti‐PD‐1 presentation. This strategy elicits robust antitumor responses, promotes immunogenic tumor cell death, suppresses lung metastasis in vivo, and provides a modular,
Alba Ortuño‐Bernal, Sandra Clara‐Trujillo, Elena Lucena‐Sánchez, Francisco J. Hicke, Andrea Escudero, Sandra Pradana‐López, Nelia Jiménez‐Alduan, Paula Díez, Alba García‐Fernández, Ramón Martínez‐Máñez   +9 more
wiley   +1 more source

Abundance gradients and their evolution in the Milky Way disk [PDF]

, 2000
J. L. Hou, Nikos Prantzos, S. Boissier
openalex   +1 more source

An Ultrapotent, Ultraeconomical, Antifreeze Polypeptide

Advanced Materials, EarlyView.
Simple and inexpensive polypeptides composed of random copolymers of alanine and glutamic acid are effective antifreezes for applications in foods and biomedicine. The polypeptides, inspired by natural extremophile proteins, inhibit the growth of large ice crystals and prevent damage to sensitive biologics.
Thomas J. McPartlon, Charles T. Osborne, Ke Wang, Rachel E. Detwiler, Konrad Meister, Jessica R. Kramer   +5 more
wiley   +1 more source

A Measurement of the Assembly of Milky Way Analogs at Redshifts 0.5 < z < 2 with Resolved Stellar Mass and Star Formation Rate Profiles

The Astrophysical Journal
The resolved mass assembly of Milky Way–mass galaxies has been previously studied in simulations, the local Universe, and at higher redshifts using infrared (IR) light profiles.
Vivian Yun Yan Tan, Adam Muzzin, Danilo Marchesini, Visal Sok, Ghassan T. E. Sarrouh, Z. Cemile Marsan   +5 more
doaj   +1 more source

Light element abundance inhomogeneities in globular clusters: probing star formation and evolution in the early Milky Way [PDF]

, 1994
Michael M. Briley, Roger A. Bell, James E. Hesser, Graeme H. Smith   +3 more
openalex   +1 more source

Deciphering the evolution of the Milky Way discs: Gaia APOGEE Kepler giant stars and the Besançon Galaxy Model [PDF]

, 2021
Lagarde N, C. Reylé, Cristina Chiappini, R. Mor, F. Anders, F. Figueras, A Miglio, M. Romero-Gómez, T. Antoja, N. Cabral, J B Salomon, A. C. Robin, Olivier Bienaymé, C. Soubiran, D. Cornu, J. Montillaud, Lagarde N, C. Reylé, Cristina Chiappini, R. Mor, F. Anders, F. Figueras, A Miglio, M. Romero-Gómez, T. Antoja, N. Cabral, J B Salomon, A. C. Robin, Olivier Bienaymé, C. Soubiran, J. Montillaud   +30 more
openalex   +1 more source

LDI, A Lipid Droplet Inhibitor, Disrupts Lipid Accumulation and Modulates Hepatic Lipid Profiles in Fatty Liver

Advanced Materials, EarlyView.
The lipid droplet inhibitor (LDI), templated with large‐pore mesoporous silica and functionalized with PKCα C1A and lipase, targets lipid degradation in fatty liver. The LDI maintains stable association with lipid droplets, thereby suppressing their formation and expansion.
Seunghee Kim, Yeojin Kim, Sanjita Paudel, In Young Kang, Suyeon Kim, Jeesoo Kim, Sunmi Park, Seung‐Hoi Koo, Hyun Sung Kim, Dae Won Jun, Jinyoung Park, Hyunbeom Lee, Joonseok Lee   +12 more
wiley   +1 more source

"Fermi" bubbles are bursting from our galaxy. Their origins remain a mystery. [PDF]

Proc Natl Acad Sci U S A, 2023
Mann A.
europepmc   +1 more source

ATLAS Probe: Breakthrough Science of Galaxy Evolution, Cosmology, Milky Way, and the Solar System

, 2019
Mark Dickinson, Lynne A. Hillenbrand, Massimo Robberto, L. Armus, M. Ballardini, Robert H. Barkhouser, J. Bartlett, Peter Behroozi, Robert A. Benjamin, J. Brinchmann, Ranga‐Ram Chary, Chia-Hsun Chuang, A. Cimatti, Charlie Conroy, E. Daddi, Megan Donahue, J. M. Diego, R. Demarco, Henry C. Ferguson, Andreas L. Faisst, Wesley C. Fraser, Karl Glazebrook, V. Gorjian, G. Hélou, Chris Hirata, Michael J. Hudson, J. Davy Kirkpatrick, Sangeeta Malhotra, Shiyue Mei, L. Moscardini, Jeffrey A. Newman, Zoran Ninkov, Álvaro Orsi, Michael E. Ressler, J. Rhoads, Jason Rhodes, Russell E. Ryan, Lado Samushia, Claudia Scarlata, D. Scolnic, Didier Ferrand, Alice E. Shapley, Décio Ferreira, Francesco Valentino, Dmitry Vorobiev, Risa H. Wechsler   +45 more
openalex   +2 more sources

The galactic habitable zone of the Milky Way and M31 from chemical evolution models with gas radial flows [PDF]

, 2014
E. Spitoni, F. Matteuccí, A. Sozzetti
openalex   +1 more source