Results 101 to 110 of about 92,409 (330)
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
What Is Missing from the Local Stellar Halo?
The Milky Way’s stellar halo, which extends to >100 kpc, encodes the evolutionary history of our Galaxy. However, most studies of the halo to date have been limited to within a few kiloparsecs of the Sun.
Katherine Sharpe +2 more
doaj +1 more source
Bar formation in the Milky Way type galaxies
8 pages, 5 ...
Polyachenko, E. V. +2 more
openaire +2 more sources
Star formation in the large Magellanic cloud [PDF]
What role the Large Magellanic Cloud (LMC), a dwarf irregular galaxy, plays in understanding infrared luminous galaxies is discussed. There are two main reasons the LMC may prove helpful.
Harvey, Paul M. +2 more
core +1 more source
Star formation history in the solar neighborhood: the link between stars and cosmology
Using a cosmological galactic evolutionary approach to model the Milky Way, we calculate the star formation history (SFH) of the solar neighborhood. The good agreement we obtain with the observational inferences suggests that our physical model describes
C Chiosi +18 more
core +2 more sources
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
We present a comprehensive study of the kinematic properties of the different Galactic disk populations, as defined by the chemical abundance ratios and stellar ages, across a large disk volume (4.5 ≤ R ≤ 15.0 kpc and ∣ Z ∣ ≤ 3.0 kpc), by using the ...
Weixiang Sun +7 more
doaj +1 more source
Are dSph galaxies Galactic building blocks?
Dwarf spheroidal galaxies (dSph) are frequently assumed to represent surviving examples of a vast now destroyed population of small systems in which many of the stars now forming the Milky Way were formed. Ongoing accretion and considerable sub-structure
Gilmore G., Asiri H.M.
doaj +1 more source
Cosmological pseudobulge formation
Bulges can be classified into classical and pseudobulges; the former are considered to be end products of galactic mergers and the latter to form via secular evolution of galactic disks.
Okamoto, Takashi
core +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source

