Results 81 to 90 of about 9,540,019 (262)

What Is Missing from the Local Stellar Halo?

open access: yesThe Astrophysical Journal
The Milky Way’s stellar halo, which extends to >100 kpc, encodes the evolutionary history of our Galaxy. However, most studies of the halo to date have been limited to within a few kiloparsecs of the Sun.
Katherine Sharpe   +2 more
doaj   +1 more source

Stellar archaeology in the Milky Way halo. Variable stars and stellar populations in the new Milky Way ultra-faint dwarfs [PDF]

open access: yes, 2015
We summarize results from the photometric survey of a number of ultra-faint dwarf satellites of the Milky Way. We are studying these systems in a systematic way to characterize their stellar populations and structural parameters, as well as their ...
MARCONI, Marcella   +9 more
core  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Mapping the Galactic Disk with the LAMOST and Gaia Red Clump Sample. VIII. Mapping the Kinematics of the Galactic Disk Using Mono-age and Mono-abundance Stellar Populations

open access: yesThe Astrophysical Journal
We present a comprehensive study of the kinematic properties of the different Galactic disk populations, as defined by the chemical abundance ratios and stellar ages, across a large disk volume (4.5 ≤ R ≤ 15.0 kpc and ∣ Z ∣ ≤ 3.0 kpc), by using the ...
Weixiang Sun   +7 more
doaj   +1 more source

Modeling Dwarf Satellites Of The Milky Way

open access: yes, 2020
Dwarf galaxies are the most abundant type of galaxies in the universe. They are the building blocks of hierarchical structure formation, and their shallow gravitational potentials make them extremely sensitive to internal and environmental
Weerasooriya, Sachithra Ishani
core  

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

open access: yesFEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav   +4 more
wiley   +1 more source

Accurate, Precise, and Physically Self-consistent Ages and Metallicities for 400,000 Solar Neighborhood Subgiant Branch Stars

open access: yesThe Astrophysical Journal
Age is the most difficult fundamental stellar parameter to infer for isolated stars. While isochrone-based ages are in general imprecise for both main-sequence dwarfs and red giants, precise isochrone-based ages can be obtained for stars on the subgiant ...
David M. Nataf   +3 more
doaj   +1 more source

Are dSph galaxies Galactic building blocks?

open access: yesEPJ Web of Conferences, 2012
Dwarf spheroidal galaxies (dSph) are frequently assumed to represent surviving examples of a vast now destroyed population of small systems in which many of the stars now forming the Milky Way were formed. Ongoing accretion and considerable sub-structure
Gilmore G., Asiri H.M.
doaj   +1 more source

At the Heart of the Milky Way

open access: yes, 2005
The authors discuss how the center of the Milky Way provides the foundation for understanding phenomena in other galaxies. The central black hole and regions of intense star formation in its vicinity can be probed at 100 times the resolution of even the ...
Lazio, T. Joseph W., La Rosa, Ted
core   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

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