Results 81 to 90 of about 8,310 (262)

Mapping the Galactic Disk with the LAMOST and Gaia Red Clump Sample. VIII. Mapping the Kinematics of the Galactic Disk Using Mono-age and Mono-abundance Stellar Populations

open access: yesThe Astrophysical Journal
We present a comprehensive study of the kinematic properties of the different Galactic disk populations, as defined by the chemical abundance ratios and stellar ages, across a large disk volume (4.5 ≤ R ≤ 15.0 kpc and ∣ Z ∣ ≤ 3.0 kpc), by using the ...
Weixiang Sun   +7 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Accurate, Precise, and Physically Self-consistent Ages and Metallicities for 400,000 Solar Neighborhood Subgiant Branch Stars

open access: yesThe Astrophysical Journal
Age is the most difficult fundamental stellar parameter to infer for isolated stars. While isochrone-based ages are in general imprecise for both main-sequence dwarfs and red giants, precise isochrone-based ages can be obtained for stars on the subgiant ...
David M. Nataf   +3 more
doaj   +1 more source

Are dSph galaxies Galactic building blocks?

open access: yesEPJ Web of Conferences, 2012
Dwarf spheroidal galaxies (dSph) are frequently assumed to represent surviving examples of a vast now destroyed population of small systems in which many of the stars now forming the Milky Way were formed. Ongoing accretion and considerable sub-structure
Gilmore G., Asiri H.M.
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

Rising from the Ashes: A Metallicity-dependent Star Formation Gap Splits the Milky Way’s α Sequences

open access: yesThe Astrophysical Journal
The elemental abundance distribution of stars encodes the history of the gas-phase abundance in the Milky Way. Without a large, unbiased sample of highly precise stellar ages, the exact timing and nature of this history must be inferred from the ...
Angus Beane
doaj   +1 more source

The Formation of the Milky Way Nuclear Cluster

open access: yes, 2011
4 pages, 4 figures, To appear in "Advances in Computational Astrophysics: methods, tools and outcomes", ASP Conference Series, R. Capuzzo-Dolcetta, M. Limongi and A.
A. Mastrobuono Battisti   +1 more
openaire   +3 more sources

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

True Pair-instability Supernova Descendant: Implications for the First Stars’ Mass Distribution

open access: yesThe Astrophysical Journal Letters
The initial mass function (IMF) of the first Population III (Pop III) stars remains a persistent mystery. Their predicted massive nature implies the existence of stars exploding as pair-instability supernovae (PISNe), but no observational evidence had ...
Ioanna Koutsouridou   +2 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

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