Results 101 to 110 of about 9,204,018 (295)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Charting our Uncharted Milky Way

open access: yes, 2020
Our position in the Milky Way, buried within its disk, makes it extraordinarily difficult to piece together the structure of our home Galaxy. We know the Milky Way is a barred spiral but many questions, including the precise number, location, and ...
Zucker, Catherine
core   +4 more sources

The Extremely Metal-rich Knot of Stars at the Heart of the Galaxy

open access: yesThe Astrophysical Journal
We show with Gaia XP spectroscopy that extremely metal-rich (EMR) stars in the Milky Way ([M/H] _XP ≳ 0.5) are largely confined to a tight “knot” at the center of the Galaxy. This EMR knot is round in projection, has a fairly abrupt edge near R _GC,proj ∼
Hans-Walter Rix   +17 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Molecular clouds and star formation in the Milky Way [PDF]

open access: yes, 2018
Using molecular line observations, this thesis studied the molecular clouds of three typical regions of the Milky Way, which are the Galactic centre, high Galactic latitudes, and the Galactic plane.
Qingzeng Yan (23497840)
core   +1 more source

Unraveling the History of the Milky Way

open access: yes, 2018
Understanding physical processes responsible for the formation and evolution of galaxies like the Milky Way is a fundamental problem in astrophysics. However, a key challenge is that the properties and orbits of the stars can only be observed at present.
Ting, Yuan-Sen
core   +4 more sources

What Is Missing from the Local Stellar Halo?

open access: yesThe Astrophysical Journal
The Milky Way’s stellar halo, which extends to >100 kpc, encodes the evolutionary history of our Galaxy. However, most studies of the halo to date have been limited to within a few kiloparsecs of the Sun.
Katherine Sharpe   +2 more
doaj   +1 more source

Molecular gas and star formation in the Milky Way

open access: yesEPJ Web of Conferences, 2012
The dense molecular gas is the ideal tracer of the spiral structure in the Milky Way, and should be used intensively to solve the puzzle of its structure. In spite of our position inside the plane, we can hope to disentangle the structures, with position-
Combes F.
doaj   +1 more source

Memorie della The Milky Way Formation Timescale

open access: yes, 2020
. Based on a new large, homogeneous photometric database of 69 Galactic globular clusters extended out to 42 kpc from the galactic center, a set of distance and reddening free relative age indicators has been measured: δ(V − I) @2.5 and ∆V HB TO .
I Saviane   +4 more
core  

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

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