Results 91 to 100 of about 9,204,018 (295)

History of star formation and chemical enrichment in the Milky Way disk

open access: yes, 2002
Based on a physical treatment of the star formation law similar to that given by Efstathiou, we have improved our two-component chemical evolution model for the Milky Way disk. Two gas infall rates are compared, one exponential, one Gaussian. It is shown
Shu, CG, Chang, RX, Hou, JL
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Chemo-dynamical simulations of the Milky Way

open access: yes, 2004
Using a state of the art galaxy formation software package, GCD+, we model the formation and evolution of galaxies which resemble our own Galaxy, the Milky Way.
Chris B. Brook (6904541)
core   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

The epoch of bar formation in the Milky Way

open access: yes, 2023
A key event in the life of the Milky Way is the formation of the bar. The Milky Way bar has restructured the disc, been slowed by the dark matter halo and funnelled gas towards the Galactic Centre. It is then important to know the period of time over which these processes have been effective.
openaire   +2 more sources

Formation Of The Milky Way

open access: yes, 2007
We review observational evidence bearing on the formation of a prototypical large spiral galaxy, the Milky Way. New ground- and space-based studies of globular star clusters and dwarf spheroidal galaxies provide a wealth of information to constrain ...
P. B. Stetson   +8 more
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Estimating the Initial Mass of the Gaia–Enceladus Dwarf Galaxy with a Chemical Evolution Model

open access: yesThe Astrophysical Journal
This work investigates the initial mass and chemical evolution history of the Gaia–Enceladus dwarf galaxy. We combine spectroscopic data from APOGEE with astrometric data from Gaia Data Release 3 to identify Gaia–Enceladus candidate stars via a machine ...
Olcay Plevne, Furkan Akbaba
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Mass Distribution and Bulge Formation in the Milky Way Galaxy [PDF]

open access: yesEAS Publications Series, 2006
Eight pages, one figure. Invited Review, Proceedings of 21st IAP Colloquium, 'Mass Profiles and Shapes of Cosmological Structures', eds. G.
openaire   +3 more sources

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