Results 71 to 80 of about 8,310 (262)
The Milky Way and other spiral galaxies
Cosmologists have often considered the Milky Way as a typical spiral galaxy, and its properties have considerably influenced the current scheme of galaxy formation.
Wang J.L. +5 more
doaj +1 more source
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
The epoch of bar formation in the Milky Way
A key event in the life of the Milky Way is the formation of the bar. The Milky Way bar has restructured the disc, been slowed by the dark matter halo and funnelled gas towards the Galactic Centre. It is then important to know the period of time over which these processes have been effective.
openaire +2 more sources
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
The Extremely Metal-rich Knot of Stars at the Heart of the Galaxy
We show with Gaia XP spectroscopy that extremely metal-rich (EMR) stars in the Milky Way ([M/H] _XP ≳ 0.5) are largely confined to a tight “knot” at the center of the Galaxy. This EMR knot is round in projection, has a fairly abrupt edge near R _GC,proj ∼
Hans-Walter Rix +17 more
doaj +1 more source
Mass Distribution and Bulge Formation in the Milky Way Galaxy [PDF]
Eight pages, one figure. Invited Review, Proceedings of 21st IAP Colloquium, 'Mass Profiles and Shapes of Cosmological Structures', eds. G.
openaire +3 more sources
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
What Is Missing from the Local Stellar Halo?
The Milky Way’s stellar halo, which extends to >100 kpc, encodes the evolutionary history of our Galaxy. However, most studies of the halo to date have been limited to within a few kiloparsecs of the Sun.
Katherine Sharpe +2 more
doaj +1 more source
Molecular gas and star formation in the Milky Way
The dense molecular gas is the ideal tracer of the spiral structure in the Milky Way, and should be used intensively to solve the puzzle of its structure. In spite of our position inside the plane, we can hope to disentangle the structures, with position-
Combes F.
doaj +1 more source
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source

