Results 51 to 60 of about 9,204,018 (295)

Andromeda and the Milky Way: Twin sisters, distant relations, or strangers in the night?

open access: yes, 2012
I summarize some recent key results from the Pan-Andromeda Archaeological Survey (PAndAS), in particular showing how recent discoveries in and around M31 compare to the known structure of the Milky Way and its satellite ...
Richardson J.   +11 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Candidate Members of the VMP/EMP Disk System of the Galaxy from the SkyMapper and SAGES Surveys

open access: yesThe Astrophysical Journal Supplement Series
Photometric stellar surveys now cover a large fraction of the sky, probe to fainter magnitudes than large-scale spectroscopic surveys, and are relatively free from the target selection biases often associated with such studies.
Jihye Hong   +17 more
doaj   +1 more source

Early formation and recent starburst activity in the nuclear disk of the Milky Way [PDF]

open access: yes, 2020
The nuclear disk is a dense stellar structure at the centre of the Milky Way, with a radius of ~150 pc (ref. 1). It has been a place of intense star formation in the past several tens of millions of years1-3, but its overall formation history has ...
Girard, Julien H. V.   +12 more
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Additional Evidence for the Existence of a Primordial Disk System

open access: yesThe Astrophysical Journal
The origin of very metal-poor (VMP; [Fe/H] ≤ −2.0) stars on planar orbits has been the subject of great attention since their first discovery. However, prior to the release of the Gaia BP/RP (XP) spectra and large photometric samples such as SkyMapper ...
Shuai Xu   +9 more
doaj   +1 more source

A Tilt in the Dark Matter Halo of the Galaxy

open access: yesThe Astrophysical Journal, 2022
Recent observations of the stellar halo have uncovered the debris of an ancient merger, Gaia–Sausage–Enceladus (GSE), estimated to have occurred ≳8 Gyr ago.
Jiwon Jesse Han   +11 more
doaj   +1 more source

Star Formation in the Local Milky Way [PDF]

open access: yesProceedings of the International Astronomical Union, 2015
AbstractStudies of molecular clouds and young stars near the sun have provided invaluable insights into the process of star formation. Indeed, much of our physical understanding of this topic has been derived from such studies. Perhaps the two most fundamental problems confronting star formation research today are: 1) determining the origin of stellar ...
openaire   +2 more sources

How Does Feedback Affect Milky Way Satellite Formation?

open access: yes, 2011
We use sub-parsec resolution hydrodynamic resimulations of a Milky Way (MW) like galaxy at high redshift to investigate the formation of the MW satellite galaxies.
Slyz, A   +5 more
core   +1 more source

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