Results 31 to 40 of about 8,310 (262)

Dawn of the Milky Way Disk: Determination of When a Rotationally Supported Disk Appears and Dating the Spin-up of the Disk

open access: yesThe Astrophysical Journal Letters
Spiral galaxies, like the Milky Way, transform at some point in time into a rotationally supported system. Using an extant dataset consisting of 319,835 subgiants from LAMOST with precise ages from the literature, we determine, for the first time, the ...
Sofia Feltzing   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

GASTRO Library. II. Exploring Chemical Bimodalities in Disk Galaxies with GSE-like Mergers and Massive Star-forming Clumps

open access: yesThe Astrophysical Journal
We use several smoothed particle hydrodynamics+ N -body models as part of the GASTRO library to study the role of high-density star-forming clumpy regions and a single merger on the formation of the α -rich and α -poor populations in the disk galaxies ...
João A. S. Amarante   +12 more
doaj   +1 more source

The Formation of the Milky Way Disk

open access: yes, 2000
We present theoretical results on the galactic abundance gradients of several chemical species for the Milky Way disk, obtained using an improved version of the two-infall model of Chiappini, Matteucci, & Gratton (1997) that incorporates a more realistic model of the galactic halo and disk.
Chiappini, Cristina   +2 more
openaire   +2 more sources

Star Formation in the Local Milky Way [PDF]

open access: yesProceedings of the International Astronomical Union, 2015
AbstractStudies of molecular clouds and young stars near the sun have provided invaluable insights into the process of star formation. Indeed, much of our physical understanding of this topic has been derived from such studies. Perhaps the two most fundamental problems confronting star formation research today are: 1) determining the origin of stellar ...
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The Three-phase Evolution of the Milky Way

open access: yesThe Astrophysical Journal
We illustrate the formation and evolution of the Milky Way over cosmic time, utilizing a sample of 10 million red giant stars with full chemodynamical information, including metallicities and α -abundances from low-resolution Gaia XP spectra.
Vedant Chandra   +8 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

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