Results 41 to 50 of about 9,204,018 (295)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The Star Formation Rate of the Milky Way as Seen by Herschel

The Astrophysical Journal, 2022
Abstract We present a new derivation of the Milky Way’s current star formation rate (SFR) based on the data of the Herschel InfraRed Galactic Plane Survey (Hi-GAL). We estimate the distribution of the SFR across the Galactic plane from the star-forming clumps identified in the Hi-GAL survey and calculate the total SFR from the sum of ...
D. Elia, S. Molinari, E. Schisano, J. D. Soler, M. Merello, D. Russeil, M. Veneziani, A. Zavagno, A. Noriega-Crespo, L. Olmi, M. Benedettini, P. Hennebelle, R. S. Klessen, S. Leurini, R. Paladini, S. Pezzuto, A. Traficante, D. J. Eden, P. G. Martin, M. Sormani, A. Coletta, T. Colman, R. Plume, Y. Maruccia, C. Mininni, S. J. Liu   +25 more
openaire   +5 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

GASTRO Library. II. Exploring Chemical Bimodalities in Disk Galaxies with GSE-like Mergers and Massive Star-forming Clumps

The Astrophysical Journal
We use several smoothed particle hydrodynamics+ N -body models as part of the GASTRO library to study the role of high-density star-forming clumpy regions and a single merger on the formation of the α -rich and α -poor populations in the disk galaxies ...
João A. S. Amarante, Chervin F. P. Laporte, Victor P. Debattista, Leandro Beraldo e Silva, Guilherme Limberg, Hélio D. Perottoni, Zhao-Yu Li, Lais Borbolato, Karl Fiteni, Chengye Cao, Nathan Deg, Tigran Khachaturyants, Xiaojie Liao   +12 more
doaj   +1 more source

ORIGIN AND EVOLUTION OF THE ABUNDANCE GRADIENT ALONG THE MILKY WAY DISK

, 2009
Based on a simple model of the chemical evolution of the Milky Way disk, we investigate the disk oxygen abundance gradient and its time evolution. Two star formation rates (SFRs) are considered, one is the classical Kennicutt-Schmidt law (Psi = 0.25 ...
Chang, R. X., Yin, J., Hou, J. L., Fu, J.   +3 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

The Three-phase Evolution of the Milky Way

The Astrophysical Journal
We illustrate the formation and evolution of the Milky Way over cosmic time, utilizing a sample of 10 million red giant stars with full chemodynamical information, including metallicities and α -abundances from low-resolution Gaia XP spectra.
Vedant Chandra, Vadim A. Semenov, Hans-Walter Rix, Charlie Conroy, Ana Bonaca, Rohan P. Naidu, René Andrae, Jiadong Li, Lars Hernquist   +8 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

The Milky Way as a Star Formation Engine [PDF]

, 2014
The cycling of material from the interstellar medium (ISM) into stars and the return of stellar ejecta into the ISM is the engine that drives the "galactic ecology" in normal spirals, a cornerstone in the formation and evolution of galaxies through cosmic time.
Molinari, S., Bally, J., Glover, S., Moore, T., Noriega-Crespo, A., Plume, R., Testi, L., Vázquez-Semadeni, E., Zavagno, A., Bernard, J. -P., Martin, P.   +10 more
openaire   +3 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source