Results 121 to 130 of about 6,401,648 (288)

Shear‐Isolating Actuation System for Exosuit Using Movable Pulley With Webbing‐Driven Mechanism

Advanced Robotics Research, EarlyView.
Tendon‐driven exosuits can chafe the skin because the moving tendon slides against the wearer. A shear‐isolating actuation system combining a movable pulley with flat‐profile webbing keeps the body‐contacting tendon layer stationary, relocating relative motion away from the skin. The compact 145‐g actuator delivers 150 N of assistance, and benchtop and
Kyeongmin Lim, Gijoon Song, Jaewook Ryu, Sangeui Lee, Junyoung Moon, Giuk Lee   +5 more
wiley   +1 more source

Impact of venous thromboembolism on mortality in hospitalized patients with inflammatory bowel disease: analysis of the MIMIC-IV database, 2008 to 2022

BMC Gastroenterology
Background Inflammatory bowel disease (IBD)is associated with extraintestinal manifestations, notably venous thromboembolism (VTE), a major cause of morbidity and mortality.
Kuang-Te Wang, Min-I Su, Wei-Ru Chiou, Chuan-Lei Chao, Yi-Fan Huang, Chun-Han Cheng   +5 more
doaj   +1 more source

A multi-omics study of magnesium sulfate to improve prognosis in sepsis-related encephalopathy: integrating clinical data-driven network pharmacology

Frontiers in Cellular and Infection Microbiology
BackgroundSepsis-associated encephalopathy (SAE) constitutes a significant neurological manifestation of sepsis, characterized by high mortality rates and posing a critical threat to patient outcomes. Magnesium sulfate has multiple effects in the nervous
Yingming Kong, Yanghao Tai, Bin Chen, Meng Zhang, Haoyu Ji, Rongke Feng, Liang Shi, Hao Chen, Hao Chen   +8 more
doaj   +1 more source

Thiamine administration and in-hospital mortality in patients with traumatic brain injury: analysis of the MIMIC-IV database

Frontiers in Neurology
AimSeveral studies have suggested the favorable impact of thiamine administration on the prognosis of diseases. However, the value of thiamine in patients with traumatic brain injury (TBI) admitted to the intensive care unit (ICU) remains unclear. The aim of this study was to investigate the association between the between thiamine administration and ...
Shuangqi Gao, Zhendan Zhu, Wenhan Zheng
openaire   +3 more sources

Chemical Screening Identifies Danofloxacin as a Self‐Renewal Agonist of Embryonic Stem Cells through Alleviation of HDAC1‐Mediated Deacetylation of Tert and Prdm10

Advanced Science, EarlyView.
This study identified Danofloxacin as a novel supporter of the maintenance of mouse embryonic stem cell (ESC) pluripotency. It functions partially by inhibiting HDAC1, which increases specific histone acetylation marks and activates key genes like Tert and Prdm10.
Yan Zhang, Junxiang Ji, Baoxing Dong, Zhenhua Zhu, Xucheng Lv, Peng Chen, Wenqiang Liu, Min Zhou, Shou‐Dong Ye   +8 more
wiley   +1 more source

Analysis of the correlation between the group-based trajectory modeling of serum osmolality and prognosis in patients with sepsis-associated encephalopathy at 72 h after admission

BMC Infectious Diseases
Background This study aimed to identify distinct trajectories of serum osmolality within the first 72 h for patients with sepsis-associated encephalopathy (SAE) in the MIMIC-IV and eICU-CRD databases and assess their impact on mortality and adverse ...
Wentao Wu, Chen Wang, Yuhua Zhang, Yongpeng Xie, Xiaomin Li   +4 more
doaj   +1 more source

Predicting In-Hospital Mortality in Myocardial Infarction: A Nomogram-Based Retrospective Analysis of the MIMIC-IV Database

Vascular Health and Risk Management
Despite significant advancements in early reperfusion therapy and pharmacological treatment, which have reduced mortality rates after myocardial infarction in recent decades, the in-hospital mortality rate remains high due to factors such as rapid disease progression, comorbid conditions, and potential complications.
Shixuan Peng, Qisheng Chen, Weiqi Ke, Yongjun Wu   +3 more
openaire   +4 more sources

Reproducibility in MIMIC v0.3.0

, 2017
<p>Added mimic-code as a submodule.</p ...
Alistair Johnson, Alistair Johnson (5279666)   +1 more
core   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Association between stress hyperglycemia ratio and all-cause mortality in critically ill patients with sepsis: results from the MIMIC-IV database

European Journal of Medical Research
Background This study aimed to explore the association between the stress hyperglycemia ratio (SHR) and short- and long-term outcomes in critically ill patients with sepsis.
Shijie Zhang, Hechen Shen, Yuchao Wang, Meng Ning, Jianghui Zhou, Xiaoyu Liang, Yun Chang, Wenqing Gao, Tong Li   +8 more
doaj   +1 more source