Results 61 to 70 of about 444,284 (257)

A generalizable and interpretable model for mortality risk stratification of sepsis patients in intensive care unit

open access: yesBMC Medical Informatics and Decision Making, 2023
Purpose This study aimed to construct a mortality model for the risk stratification of intensive care unit (ICU) patients with sepsis by applying a machine learning algorithm.
Jinhu Zhuang   +5 more
doaj   +1 more source

The effects of floral mimics and models on each others' fitness [PDF]

open access: yesProceedings of the Royal Society B: Biological Sciences, 2006
Plants that lack floral rewards may nevertheless attract pollinators by mimicking the flowers of rewarding plants. It has been suggested that both mimics and models should suffer reduced fitness when mimics are abundant relative to their models.
Bruce, Anderson, Steven D, Johnson
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

AN ANALYSIS OF THE SHADOW ECONOMY IN EU COUNTRIES [PDF]

open access: yesCES Working Papers, 2016
The paper aims at analysing the dimension of the underground economy in the EU states between 2003 and 2015. In order to achieve this goal, we use qualitative and quantitative methods. In the first two sections of the study we resort to conceptualisation
Brindusa Mihaela Tudose   +1 more
doaj  

Predicting acute kidney injury risk in acute myocardial infarction patients: An artificial intelligence model using medical information mart for intensive care databases

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundPredictive models based on machine learning have been widely used in clinical practice. Patients with acute myocardial infarction (AMI) are prone to the risk of acute kidney injury (AKI), which results in a poor prognosis for the patient.
Dabei Cai   +13 more
doaj   +1 more source

A vascularized model of the human liver mimics regenerative responses

open access: yesProceedings of the National Academy of Sciences, 2022
Liver regeneration is a well-orchestrated process that is typically studied in animal models. Although previous animal studies have offered many insights into liver regeneration, human biology is less well understood. To this end, we developed a three-dimensional (3D) platform called structurally vascularized hepatic ensembles for analyzing ...
Chhabra, Arnav   +6 more
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Cross-cultural adaptation and factor structure investigation of the Marital Forgiveness Scale

open access: yesPsikohumaniora: Jurnal Penelitian Psikologi
Forgiveness is essential in marriage as it can bring a sense of satisfaction to married life. This study aims to adapt and examine the factor structure of the Marital Forgiveness Scale (MFS), a forgiveness instrument in the context of marriage. After the
Endah Puspita Sari   +2 more
doaj   +1 more source

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