Evolution of Ocular Organ‐On‐Chip Systems for Disease Modelling and Drug Testing: Where are We Now?
The rise in ophthalmic diseases due to aging, screen use, and environmental factors has driven demand for better ocular models. Traditional systems fall short, encouraging the development of organ‐on‐chip devices. These microfluidic platforms replicate eye tissue architecture, enable drug screening, and simulate ocular diseases.
Sara Trujillo
wiley +1 more source
Every "Body" Gets a Say: An Augmented Optimization Metric to Preserve Body Pose During Avatar Adaptation in Mixed/Augmented Reality. [PDF]
Watkins A, Ullal A, Sarkar N.
europepmc +1 more source
Antiidiotypic antibody mimicry of a bluetongue virus neutralizing antigen. [PDF]
Franziska B. Grieder, Kevin T. Schultz
openalex +1 more source
NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea
This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi+16 more
wiley +1 more source
A novel vasculogenic mimicry-related nomogram predicts prognosis in hepatocellular carcinoma. [PDF]
Zhong Y+5 more
europepmc +1 more source
Autoantibodies to the alpha/beta T-cell receptors in human immunodeficiency virus infection: dysregulation and mimicry. [PDF]
Douglas F. Lake+5 more
openalex +1 more source
LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing
This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang+15 more
wiley +1 more source
Similarity to Self-Antigens Shapes Epitope Recognition from Viruses Under Autoimmune and Infectious Disease. [PDF]
Ras-Carmona A, Lehmann A, Reche PA.
europepmc +1 more source
Possible Mimicry between Certain Carabidae and Chrysomelidae
Edward U. Balsbaugh
openalex +2 more sources