Results 241 to 250 of about 57,697 (301)

Modulation of Network Plasticity Opens Novel Therapeutic Possibilities in Cancer, Diabetes, and Neurodegeneration

open access: yesAdvanced Science, EarlyView.
Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély   +5 more
wiley   +1 more source

Nanozyme Microrobots: Programmable Spatiotemporal Catalysis for Targeted Therapy and Diagnostics

open access: yesAdvanced Science, EarlyView.
This review presents nanozyme microrobots as emerging catalytic systems that integrate mobility, external actuation, and adaptive reactivity to achieve precise biochemical functions. By examining mobility‐regulated catalysis, spatial targeting, integrated designs, and translational demonstrations, the article highlights how nanozyme robotics enables ...
Hong Huy Tran   +5 more
wiley   +1 more source

Cholesterol Promotes Lung Adenocarcinoma Brain Metastasis by Stabilizing EGFR Protein to Drive EMT, Metabolic Reprogramming, and Premetastatic Niche Formation

open access: yesAdvanced Science, EarlyView.
Cholesterol is revealed as a multitasking fuel for lung adenocarcinoma brain metastasis: it locks EGFR at the membrane to sustain AKT/NF‐κB–driven glycolysis and EMT, loosens the blood–brain barrier by promoting Claudin‐5 loss, and rewires microglia through IL‐4R lipid‐raft–JAK1/STAT6 signaling.
Ying Chen   +14 more
wiley   +1 more source

The spread of mind: psychological contagion in theory and critique. [PDF]

open access: yesFront Psychol
Houran J   +3 more
europepmc   +1 more source

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