Results 41 to 50 of about 157,374 (289)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Active Choice of Teachers, Learning Strategies and Goals for a Socially Guided Intrinsic Motivation Learner

open access: yesPaladyn, 2012
We present an active learning architecture that allows a robot to actively learn which data collection strategy is most efficient for acquiring motor skills to achieve multiple outcomes, and generalise over its experience to achieve new outcomes.
Nguyen Sao Mai, Oudeyer Pierre-Yves
doaj   +1 more source

Autoimmunity in Chronic Chagas Disease: A Road of Multiple Pathways to Cardiomyopathy?

open access: yesFrontiers in Immunology, 2018
Chagas disease (CD), a neglected tropical disease caused by the protozoan Trypanosoma cruzi, affects around six million individuals in Latin America. Currently, CD occurs worldwide, becoming a significant public health concern due to its silent aspect ...
Elidiana De Bona   +7 more
doaj   +1 more source

The Cooperation Link: Power and Context Moderate Verbal Mimicry [PDF]

open access: yes, 2019
Drawing on theories of mimicry as a schema-driven process, we tested whether the degree of verbal mimicry is dependent on the congruence between interactants’ power dynamic (symmetric vs. asymmetric), task type (cooperative vs.
McKulloch, Kathleen   +3 more
core   +3 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

The association of negative mood with automatic and effortful facial expression mimicry

open access: yesFrontiers in Psychology, 2023
The natural process of mimicking the facial expressions of others is well established, as are the deficits in this reflexive behavior for individuals with clinical disorders such as depression.
Tara L. Kraft-Feil   +5 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Aposematic signaling and seasonal variation in dorsal pelage in a venomous mammal

open access: yesEcology and Evolution, 2021
In mammals, colouration patterns are often related to concealment, intraspecific communication, including aposematic signals, and physiological adaptations.
K. Anne‐Isola Nekaris   +5 more
doaj   +1 more source

Autistic traits modulate frontostriatal connectivity during processing of rewarding faces [PDF]

open access: yes, 2014
Deficits in facial mimicry have been widely reported in autism. Some studies have suggested that these deficits are restricted to spontaneous mimicry and do not extend to volitional mimicry.
Chakrabarti, B.   +3 more
core   +2 more sources

Conformational Plasticity of HLA-B27 Molecules Correlates Inversely With Efficiency of Negative T Cell Selection [PDF]

open access: yes, 2020
The development of autoimmune disorders is incompletely understood. Inefficient thymic T cell selection against self-peptides presented by major histocompatibility antigens (HLA in humans) may contribute to the emergence of auto-reactive effector cells ...
Loll, Bernhard   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy