Transition metals and oxidation reactions trigger stargate opening during the initial stages of the replicative cycle of the giant Tupanvirus [PDF]
mBioTupanviruses, members of the family Mimiviridae, infect phagocytic cells. Particle uncoating begins inside the phagosome, with capsid opening via the stargate. The mechanism through which this opening takes place is unknown.
Juliana R. Cortines +11 more
doaj +2 more sources
Expanding the Mimiviridae family using asparagine synthase as a sequence bait.
Virology, 2014 Since the pioneering Global Ocean Sampling project, large-scale sequencing of environmental DNA has become a common approach to assess the biodiversity of diverse environments, with an emphasis on microbial populations: unicellular eukaryotes ("protists"), bacteria, archaea, and their innumerous associated viruses and phages.
Michael Mozar, J. Claverie
semanticscholar +3 more sources
Presence of CRISPR CAS-Like Sequences as a Proposed Mechanism for Horizontal Genetic Exchanges between Trichomonas vaginalis and Its Associated Virus: A Comparative Genomic Analysis with the First Report of a Putative CRISPR CAS Structures in Eukaryotic Cells. [PDF]
Biomed Res Int, 2023 Introduction. Trichomonas vaginalis genome is among the largest genome size and coding capacities. Combinations of gene duplications, transposon, repeated sequences, and lateral gene transfers (LGTs) have contributed to the unexpected large genomic size and diversity. This study is aimed at investigating genomic exchange and seeking for presence of the
Kenarkoohi A +11 more
europepmc +2 more sources
Gut Virome: What's the Role in Irritable Bowel Syndrome? [PDF]
Rev Med VirolABSTRACT The gut virome, an integral but still poorly understood component of the gut microbiota, is emerging as an important player in the pathophysiology of irritable bowel syndrome (IBS). Recent evidence suggests that alterations in virome diversity and phage–bacteria interactions contribute to gut dysbiosis, immune modulation and gut barrier ...
Rettura F +6 more
europepmc +2 more sources
Comparative Genomics of Chrysochromulina Ericina Virus and Other Microalga-Infecting Large DNA Viruses Highlights Their Intricate Evolutionary Relationship with the Established Mimiviridae Family [PDF]
Journal of Virology, 2017 ABSTRACTChrysochromulina ericina virus CeV-01B (CeV) was isolated from Norwegian coastal waters in 1998. Its icosahedral particle is 160 nm in diameter and encloses a 474-kb double-stranded DNA (dsDNA) genome. This virus, although infecting a microalga (the haptophyceaeHaptolina ericina, formerlyChrysochromulina ericina), is phylogenetically related to
Lucie Gallot-Lavallée +2 more
semanticscholar +4 more sources
An efficient numerical representation of genome sequence: natural vector with covariance component [PDF]
PeerJ, 2022 Background The characterization and comparison of microbial sequences, including archaea, bacteria, viruses and fungi, are very important to understand their evolutionary origin and the population relationship.
Nan Sun, Xin Zhao, Stephen S.-T. Yau
doaj +2 more sources
Virology, 2014 Since the discovery of Mimivirus, the founding member of the family Mimiviridae, three lineages, A-C, have been delineated among the mimiviruses of amoebae. To date, all giant viruses with annotated genomes have been isolated from water samples. Here, we describe the genome of two mimiviruses, Terra1 virus and Terra2 virus, which were recovered by co ...
N. Yoosuf +6 more
semanticscholar +3 more sources
Giant Viruses as a Source of Novel Enzymes for Biotechnological Application
Pathogens, 2022 The global demand for industrial enzymes has been increasing in recent years, and the search for new sources of these biological products is intense, especially in microorganisms.
Ellen Gonçalves de Oliveira +6 more
doaj +1 more source
Insights Into Sequences of Viral and Bacterial Origin in the Metatranscriptome of Centaurea cyanus L. Susceptible and Resistant to Acetolactate Synthase (ALS)-Inhibiting Herbicides. [PDF]
Environ Microbiol RepMetatranscriptomic analysis of Centaurea cyanus revealed diverse plant‐associated viral and bacterial sequences in herbicide‐susceptible and ‐resistant biotypes. While novel partitiviruses occurred independently of resistance status, differences in bacterial community composition may suggest a potential role of the plant microbiome in responses to ...
Marcinkowska K +2 more
europepmc +2 more sources
Fecal Viral Community Responses to High-Fat Diet in Mice. [PDF]
, 2020 Alterations in diet can have significant impact on the host, with high-fat diet (HFD) leading to obesity, diabetes, and inflammation of the gut.
Blaser, Martin J +6 more
core +1 more source