Results 81 to 90 of about 169 (131)

A SYNTHESIS OF MIMOSINE

Canadian Journal of Chemistry, 1962
DL-Mimosine has been sinthesized by debenzylation and detosylation of the product obtained by condensation of 3-benzyloxy-4-pyrone with β-amino-α-tosylaminopropionic acid.A new method for the isolation of mimosine from Leucaena glauca Benth. is described.
Ian D. Spenser, Albert D. Notation
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Inhibition of Growth of Hair by Mimosine

Nature, 1962
Loss of hair in animals following ingestion of seeds and foliage of Leucaena glauca was first reported in 18971. Sudden loss of hair in native women has been ascribed to consumption of Leucaena glauca seeds2. The toxic principle contained in this plant is a water-soluble amino-acid termed leucenol, and is identical with mimosine obtained from Mimosa ...
R G, CROUNSE, J D, MAXWELL, H, BLANK
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PRECURSORS OF MIMOSINE IN MIMOSA PUDICA

Canadian Journal of Biochemistry, 1965
In Mimosa pudica L. both L- and DL-lysine serve as specific precursors of the -γ-pyridone nucleus of mimosine. Succinic acid is also incorporated into the nucleus. Glycerol and glyceric acid enter the side chain of mimosine. An improved method for the isolation of mimosine from M. pudica is described.
H P, Tiwari, I D, Spenser
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Effect of mimosine on the rat fetus

Teratology, 1970
AbstractGroups of 16 pregnant rats per treatment were fed ad libitum a basal diet containing 0, 0.3, 0.5, or 0.7% mimosine or allowed a restricted intake of the diet with no mimosine until killed on day 20 of gestation.Incremental increases of mimosine caused significant (P<0.01) decreases in daily feed consumption, weight gain per unit of food, and
S, Dewreede, O, Wayman
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Biosynthesis of mimosine

Phytochemistry, 1964
Abstract Administration of [2-14C]- dl -lysine to Leucaena glauca results in incorporation of radioactivity into mimosine, pipecolic acid and 5-hydroxypipecolic acid. Degradation of the mimosine reveals that 95% of the radioactivity is present in the pyridone ring.
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Polarographic investigation of mimosine

Recueil des Travaux Chimiques des Pays-Bas, 1950
AbstractA polarographic investigation of mimosine was made in order to obtain more information on its polar structure. The polarographic behaviour of mimosine is abnormal, but it is possible to give a reaction scheme explaining these phenomena.
Sj. L. Bonting, F. R. Schepman
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The absolute configuration of mimosine

Recueil des Travaux Chimiques des Pays-Bas, 1964
AbstractDegradation of the plant amino acid (‐)‐mimosine yielded optically pure (+)‐α,β‐diaminopropionic acid hydrobromide identical with the acid obtained from L‐asparagine. (‐)‐Mimosine therefore belongs to the Ls‐series.
H. C. Beyerman, L. Maat, M. P. Hegarty
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The inhibitory effect of mimosine on collagen synthesis

Toxicon, 1975
Abstract The effect of mimosine [β-N(3-hydroxy-4-pyridone)-α-amino propionic acid] on the biosynthesis of collagen has been studied in embryonic cartilage. The synthesis of hydroxyproline-14C was markedly inhibited in the presence of 1 mM mimosine. Autoradiographs of embryonic cartilage indicated that when the hydroxylation of proline was inhibited ...
S Y, Tang, K H, Ling
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The Dual Effect of Mimosine on DNA Replication

Experimental Cell Research, 1997
The plant amino acid, mimosine, is an extremely effective inhibitor of DNA replication in mammalian cells, but the mechanism by which this inhibition is achieved is unknown. The drug has been proposed either to inhibit initiation at origins of replication or to inhibit chain elongation by lowering nucleotide pool levels.
R F, Kalejta, J L, Hamlin
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Metabolic effects of mimosine on tyrosine in the rat

Zeitschrift für Tierphysiologie Tierernährung und Futtermittelkunde, 1981
ZusammenfassungDer Stoffwechseleinfluß von Mimosin auf den Tyrosinspiegel in der RatteDie vorliegende, an Ratten durchgeführte Untersuchung wurde angestellt, um den Einfluß von Mimosin auf den Stoffwechsel des ihm strukturell analogen Tyrosins zu untersuchen.Im 1.
U, ter Meulen, K D, Günther, E A, El-Harith   +2 more
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