Results 41 to 50 of about 10,558 (304)

A survey dataset to identify industry practices and challenges for mine rehabilitation completion criteria in Western Australia

Data in Brief, 2021
The development of acceptable and achievable completion criteria is fundamental to the successful relinquishment of mined land to a post-mining use.
Marit E. Kragt, Ana Manero
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Informed mine closure by multi-dimensional modelling of tailings deposition and consolidation [PDF]

, 2019
This paper introduces an advanced geotechnical numerical modelling approach, which can be used to simulate the gradual deposition and large-strain consolidation of tailings in a multi-dimensional space.
Boylan, Noel, Noel Boylan, Hongjie Zhou, Zhou, Hongjie, Amodio, Alessandro, Alessandro Amodio   +5 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Analysis of the prediction and evolution process of waterfilling in closed coal mine goaf

Meitan xuebao
After coal mine closure, the groundwater level recovers, while the water accumulation process in goaf areas has rarely been studied. Taking Xuzhou Sanhejian closed coal mine as an example. Based on mine closure reports and borehole data, combined with 3D
Yanqing DING, Renhao PANG, Jing QIAN, Lihong DUAN, Taisen CHEN   +4 more
doaj   +1 more source

Sustainability of post-mining land use and ecotourism

Jurnal Perspektif Pembiayaan dan Pembangunan Daerah, 2018
The mining sector can contribute to the state in the form of foreign exchange and state in the form of foreign exchange and funding sources such as royalties, taxes, the expansion of employment and physical development, on the other hand, led to some ...
Herdis Herdiansyah, Marikha Ulfah Utami, Joko Tri Haryanto   +2 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source