Results 101 to 110 of about 5,070,469 (292)

Conditionally Significant eQTL and TWAS Analyses Identify MsRD26 as a Major Candidate Positive Regulator of Salt Tolerance in Medicago sativa L

open access: yesAdvanced Science, EarlyView.
Salt stress significantly impacts plant growth. Through population transcriptome, eQTL and TWAS analyses, we identified several candidate genes potentially associated with salt stress response. Functional assays suggested that some of these genes may contribute to salt tolerance.
Lin Chen   +12 more
wiley   +1 more source

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

open access: yesAdvanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai   +18 more
wiley   +1 more source

MetaboSense: An Integrated Quantum Dot‐Mediated Aptamer Assay and Modular Microfluidic Platform for Continuous In‐Line Monitoring of Lung Metabolism During Ex Vivo Perfusion

open access: yesAdvanced Science, EarlyView.
MetaboSense is a first‐of‐its‐kind microfluidic platform enabling continuous, in‐line monitoring of glucose and lactate during ex vivo lung perfusion. Combining a quantum dot–mediated aptamer assay with mixing, depletion, and optofluidic detection modules, it achieves 60–s temporal resolution and shows strong agreement with standard blood gas analyzers,
Sanjana Srikant   +14 more
wiley   +1 more source

Case Studies from Simulating Mine Fires in Coal Mines and Their Effects on Mine Ventilation Systems

open access: yes, 2004
The structure of a comprehensive research project into mine fires study applying the Ventgraph mine fire simulation software, preplanning of escape scenarios and general interaction with rescue responses is outlined.
Gillies, Stewart, Wu, Hsin Wei
core   +1 more source

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

open access: yesAdvanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem   +24 more
wiley   +1 more source

Ventilation Network Optimization for Deep Mines [PDF]

open access: yes, 1999
The development of underground mines in Bulgaria has reached depth limit. The conventional approach for engineering the mine ventilation is unsatisfactory under the existing level of concentration and intensification of mining work under the already ...
Shoushoulov, Georgi   +2 more
core   +1 more source

Heat Treatment and Ventilation Optimization in a Deep Mine

open access: yesAdvances in Civil Engineering, 2018
In order to address the issue of high temperatures and thermal damages in deep mines, the factors causing downhole heat damage at high temperatures were analyzed, the mine ventilation system was optimized and rebuilt, and a cooling system was established.
Xingxin Nie   +3 more
doaj   +1 more source

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

open access: yesAdvanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu   +10 more
wiley   +1 more source

Application of improved BP neural network in fault detection of mine ventilation system

open access: yesGong-kuang zidonghua, 2013
For problem that step of traditional learning algorithm of BP neural network is difficult to determine, the paper proposed a method of using BP neural network based on RLS algorithm to detect fault of mine ventilation system.
ZHANG Fei, HE Ya-qin, ZHANG Ke
doaj  

Dynamic calculation of heat-flow coupled mine ventilation network with introduction of air volume fluctuation factor

open access: yesMeitan xuebao
To address the issue of continuous multi-scale fluctuations in air volume due to the thermal flow within the unsteady airflow medium in the ventilation system pipe domain, which limits the accuracy of system state mapping when using a static thermal ...
Tong JIA, Heng MA, Ke GAO
doaj   +1 more source

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