Results 41 to 50 of about 1,189,611 (302)

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Estudo de demanda de informação no setor de geociências e tecnologia mineral

open access: yesCiência da Informação, 1986
Objetivando oferecer insumos para a criação do Sistema Nacional de lnformação em Geociências e Tecnologia Mineral realizou-se um estudo sobre a demanda de informação nesse setor baseado em uma amostra representativa de todos os segmentos a ele ligados e ...
Departamento Nacional da Produção Mineral (DNPM)
doaj  

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

The use of banquettes of Posidonia oceanica as a source of fiber and minerals in ruminant nutrition. An observational study

open access: yesAnimal, 2014
In the search for new food sources that contribute to the optimization of livestock production this paper discusses the possibility of using waste (called banquettes) of a marine plant commonly found on the Mediterranean coasts: Posidonia oceanica.
C. Castillo   +6 more
doaj   +1 more source

Associations of Rheumatoid Arthritis Disease Activity With Frailty Over Five Years of Follow‐up

open access: yesArthritis Care &Research, EarlyView.
Objective To evaluate whether rheumatoid arthritis (RA) disease activity is associated with frailty both in cross‐section and longitudinally. Methods Participants within the Veterans Affairs Rheumatoid Arthritis (VARA) registry enrolled from 2003 to 2022 were included.
Courtney N. Loecker   +14 more
wiley   +1 more source

Mineral sands in Asia and the Pacific [PDF]

open access: yes, 1985
The Mineral Resources Section of ESCAP in re[1]viewing industry data noted that minerals such as rutile, ilmenite, zircon and monazite were experiencing a strong demand and increasing prices especially during 1985.
UN.ESCAP   +1 more
core   +1 more source

Evaluation of African yam bean (Sphenostylis stenocarpa) accessions grown in Togo for nutritional and antinutritional properties

open access: yesFrontiers in Food Science and Technology
IntroductionAfrican yam bean (AYB) is a native legume crop from Africa with significant nutritional and health potential. In Togo, however, the crop remains underutilized and neglected due to a lack of awareness of its substantial potential.
Koffi Kibalou Palanga   +6 more
doaj   +1 more source

SOME CONSIDERATIONS ON THE CONCEPT OF LIFE CRYSTALLIZATION [PDF]

open access: yesМинералогия, 2015
To finish the elaboration of the concept of life crystallization suggested by Academician N.P. Yushkin, it is important to specify some definitions. We propose new formulations of the following terms: crystallization, life, mineral, cell and others.
V.A. Popov
doaj  

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