Results 51 to 60 of about 2,538,610 (251)

A Global Methane Observation System to Reduce Uncertainty for Anthropogenic and Natural Sources and Sinks for Detecting and Attributing Climate Feedbacks

Advanced Science, EarlyView.
Conceptual illustration of a Global Ecosystem Methane Observing System (GEM‐OS) integrating satellites, aircraft, atmospheric networks, and ecosystem measurements to quantify methane emissions from anthropogenic and natural sources. The multi‐scale observing framework improves source attribution, reduces uncertainty in regional methane budgets, and ...
P. Ciais, S. Peng, J. Chang, F. Li, Q. Zhu, K. Yuan, G. Hugelius, H. Li, Y. Cai, F. Chevallier, K. Tibrewal, E. A. Kort, K. Arndt, J. Watts, B. Buma, N. Besic, P. I. Palmer, H. Cadillo‐Quiroz, E. Euskirchen, M. J. Gondwe, A. Hoyt, R. Jackson, S. Malone, D. Monteverde, S. Natali, M. Ramonet, C. Rey‐Sanchez, L. B. Sagang, E. A. G. Schuur, R. Vargas, R. Varner, Z. Zhang, B. Poulter   +32 more
wiley   +1 more source

Metabolomics-based profiles predictive of low bone mass in menopausal women

Bone Reports, 2018
Osteoporosis is a skeletal disorder characterized by compromised bone strength and increased risk of fracture. Low bone mass and/or pre-existing bone fragility fractures serve as diagnostic criteria in deciding when to start medication for osteoporosis ...
Takeshi Miyamoto, Akiyoshi Hirayama, Yuiko Sato, Tami Koboyashi, Eri Katsuyama, Hiroya Kanagawa, Atsuhiro Fujie, Mayu Morita, Ryuichi Watanabe, Toshimi Tando, Kana Miyamoto, Takashi Tsuji, Atsushi Funayama, Tomoyoshi Soga, Masaru Tomita, Masaya Nakamura, Morio Matsumoto   +16 more
doaj   +1 more source

Human umbilical cord blood-derived CD34+ cells reverse osteoporosis in NOD/SCID mice by altering osteoblastic and osteoclastic activities. [PDF]

PLoS ONE, 2012
Osteoporosis is a bone disorder associated with loss of bone mineral density and micro architecture. A balance of osteoblasts and osteoclasts activities maintains bone homeostasis.
Reeva Aggarwal, Jingwei Lu, Suman Kanji, Matthew Joseph, Manjusri Das, Garrett J Noble, Brooke K McMichael, Sudha Agarwal, Richard T Hart, Zongyang Sun, Beth S Lee, Thomas J Rosol, Rebecca Jackson, Hai-Quan Mao, Vincent J Pompili, Hiranmoy Das   +15 more
doaj   +1 more source

In Situ Profiling of Nanoscale Strains Uncovers Mechano‐Architectural Predictors of Aging and Osteoarthritis Emergence

Advanced Science, EarlyView.
In situ mechanical loading of osteoarthritis‐prone murine knee joints reveals that spatial alterations in subchondral plate microarchitecture precede cartilage loss and promote a shift from coordinated epiphyseal strain dissipation in healthy joints to focal subchondral strain concentration in osteoarthritis‐prone joints.
Aikta Sharma, Lucinda A. E. Evans, Lucie E. Bourne, Jishizhan Chen, Alissa L. Parmenter, Joseph Brunet, Kamel Madi, Sebastian Marussi, Andrew A. Pitsillides, Peter D. Lee, Katherine A. Staines   +10 more
wiley   +1 more source

Effect of detraining on bone strength in subjects with chronic spinal cord injury after a period of electrically-stimulated-cycling : a small cohort study [PDF]

, 2009
To investigate adaptive changes in bone and muscle parameters in the paralysed limbs after detraining or reduced functional electrical stimulation (FES) induced cycling following high-volume FES-cycling in chronic spinal cord injury.
Hunt, Kenneth, Coupaud, Sylvie, Frotzler, Angela, Kakebeeke, Tanja, Perret, Claudio, Eser, Prisca   +5 more
core   +2 more sources

Evaluation of bone mineral density in rats administered methylphenidate

Psychiatry and Clinical Psychopharmacology, 2021
Objective: Methylphenidate is a drug which is frequently prescribed in order to cope with the symptoms of attention-deficit hyperactivity disorder.
Tümer Türkbay, Ayhan Cöngöloğlu, Hüsamettin Sargın, Ruşen Dündaröz, Teoman Söhmen   +4 more
doaj  

The global, regional, and national burden attributable to low bone mineral density, 1990–2020: an analysis of a modifiable risk factor from the Global Burden of Disease Study 2021

BACKGROUND: Fractures related to osteoporosis and low bone mineral density lead to substantial morbidity, mortality, and cost to individuals and health systems.
GBD 2021 Low Bone Mineral Density Collaborators
core   +1 more source

The IRE1‐XBP1s Axis Drives Inflammatory Osteolysis by Regulating a 5‐HT Dependent Endogenous Anti‐Autophagy Mechanism

Advanced Science, EarlyView.
A previously unrecognized IRE1‐XBP1s‐Slc6a4 signaling axis links endoplasmic reticulum stress to serotonin metabolism, autophagy, and inflammatory osteoclastogenesis. By promoting intracellular serotonin uptake and reducing endogenous 3‐methyladenine accumulation, this pathway accelerates inflammatory bone destruction and provides a promising ...
Pengchao Yang, Binxiang Zhu, Yuzhi He, Yang Tian, Honglei Kang, Shian Hu, Pengju Wang, Yong Xu, Zhuowei Lei, Peijun Qi, Hao Yang, Yang Lin, Yimin Dong, Feng Li, Hanfeng Guan   +14 more
wiley   +1 more source

CHANGE OF INDICES OF MINERAL DENSITY OF BONE TISSUE AT CHRONIC TRAUMATIC OSTEOMYELITIS

Acta Biomedica Scientifica, 2014
Comparative analysis of changes of indices of mineral density of bone tissue in patients with chronic traumatic osteomyelitis with different terms of shin synostosis, with united and ununited fractures was performed. Dependence of synostosis terms on the
S. N. Leonova
doaj  

Effect of Early Versus Late Hemodialysis On Mineral Bone Disorders [PDF]

Al-Azhar International Medical Journal
Background: Chronic kidney disease–mineral and bone disorder (CKD-MBD) is a common complication in advanced CKD, leading to disruptions in mineral metabolism, bone health, and systemic outcomes.
Osama Mohamed Ahmed, Abdel-Aleem Abdel-Aleem Ali El-Gendy, Hazem Sayed Ahmed Ayoub, Mohamed Eladl Ali Ali, Eslam saber Ahmed Taha   +4 more
doaj   +1 more source