Results 211 to 220 of about 43,749 (262)

Apparent mineralocorticoid excess

Trends in Endocrinology & Metabolism, 2001
Apparent mineralocorticoid excess (AME) is a potentially fatal genetic disorder causing severe juvenile hypertension, pre- and postnatal growth failure, hypokalemia and low to undetectable levels of renin and aldosterone. It is caused by autosomal recessive mutations in the HSD11B2 gene, which result in a deficiency of 11 beta-hydroxysteroid ...
R C, Wilson, S, Nimkarn, M I, New
openaire   +2 more sources

The Multifaceted Mineralocorticoid Receptor

Comprehensive Physiology, 2014
Abstract The primary adrenal cortical steroid hormones, aldosterone, and the glucocorticoids cortisol and corticosterone, act through the structurally similar mineralocorticoid (MR) and glucocorticoid receptors (GRs). Aldosterone is crucial for fluid, electrolyte, and hemodynamic homeostasis and tissue repair; the
Elise, Gomez-Sanchez, Celso E, Gomez-Sanchez   +1 more
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Apparent mineralocorticoid excess

The Journal of Steroid Biochemistry and Molecular Biology, 1995
Apparent mineralocorticoid excess is a syndrome reflecting the absent or impaired activity of the enzyme 11β-hydroxysteroid dehydrogenase Type 2. It may be mild when the mutant enzyme retains some activity, or severe when activity is absolutely or essentially absent.
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Mineralocorticoids and blood pressure

Current Opinion in Nephrology and Hypertension, 1994
Recent observations suggest that the syndrome of mineralocorticoid excess, primary aldosteronism, may be more common than has been previously believed. Enhanced detection of this syndrome has been simplified by the development of sensitive screening techniques.
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The role of mineralocorticoid receptor activation in kidney inflammation and fibrosis

Kidney International Supplements, 2022
Luther Jm, Agnes Fogo
exaly  

Clinical perspective—evolving evidence of mineralocorticoid receptor antagonists in patients with chronic kidney disease and type 2 diabetes

Kidney International Supplements, 2022
Peter Rossing
exaly  

Mineralocorticoids and Hypertension

American Journal of Nephrology, 2008
O B, Holland, C, Gomez-Sanchez
openaire   +2 more sources

Nonepithelial mineralocorticoid receptor activation as a determinant of kidney disease

Kidney International Supplements, 2022
Frédéric Jaisser, Jonatan Barrera-Chimal, Sophie Girerd   +2 more
exaly  

Mineralocorticoid receptor activation and antagonism in cardiovascular disease: cellular and molecular mechanisms

Kidney International Supplements, 2022
Achim Lother, Johann Bauersachs
exaly  

Mineralocorticoid hypertension

The Lancet, 1994
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