In heart failure, renin‐angiotensin system inhibitor (RASI) use was associated with less skeletal muscle wasting in patients with diabetes, but not in those without diabetes (significant interaction). The association in diabetes was more evident at lower plasma 3‐methylhistidine levels than at higher levels, suggesting a potential biomarker‐defined ...
Hidemichi Kouzu +10 more
wiley +1 more source
The Role of Aldosterone in Vascular Permeability in Diabetes. [PDF]
Aleksiejczuk M +9 more
europepmc +1 more source
ABSTRACT Intraspecific competition due to for example, density, has substantial influence on fitness dynamics and life histories, but the underlying physiological mechanisms are often complex and the molecular basis unclear. Further, designing laboratory experiments to measure physiological responses that reflect natural conditions is challenging. Here,
Morgane Frapin +8 more
wiley +1 more source
Exogenous corticosteroid-induced modulation of RAAS: potential implications for septic shock biomarker analysis. [PDF]
Uslar T +4 more
europepmc +1 more source
Acid‐sensing ion channel 1a deficiency drives endocrine hypertension in male mice
Abstract figure legend Acid‐sensing ion channel 1a deficiency drives endocrine hypertension in aged male mice. Global deletion of ASIC1a (Asic1a−/−) in adult male mice (6 months old) elevates corticosterone, leading to hypokalaemia, volume expansion, increased pulse pressure and cardiomyocyte hypertrophy.
Selina M. Garcia +9 more
wiley +1 more source
Efficacy and side effects of long-term treatment strategies of canine primary hypoadrenocorticism. [PDF]
Dobosz DA, Zablotski Y, Wehner A.
europepmc +1 more source
StAR Protein Deficiency in Clinical Practice: A Case Series From Saudi Arabia
Objectives Steroidogenic acute regulatory (StAR) protein deficiency is a rare autosomal recessive disorder that disrupts steroid hormone biosynthesis, resulting in congenital adrenal hyperplasia (CAH) and variations in sexual development. However, limited data is available in Saudi Arabia.
Abeer Alabduljabbar +6 more
wiley +1 more source
Finerenone as a Nonsteroidal Mineralocorticoid Receptor Antagonist for Lupus Nephritis. [PDF]
Sun M, Xiao F, Chen X, Wang L, Dai H.
europepmc +1 more source
The Use of Tranexamic Acid to Treat Melasma: A Systematic Review and Meta‐Analysis
Introduction Tranexamic acid (TXA) is a synthetic derivative of the amino acid lysine that inhibits bleeding due to its effects on plasminogen conversion, approved by the FDA to treat menorrhagia and prevent bleeding in hemophilia patients undergoing dental extraction.
Nabila Scabine Pessotti +7 more
wiley +1 more source
Deficiency of mineralocorticoid receptor signalling in myeloid cells protects cardiac and kidney function in hypertensive diabetic mice. [PDF]
Tesch GH +4 more
europepmc +1 more source

