Results 91 to 100 of about 2,343,081 (240)
PLoS ONE, 2020 Glucocorticoid (GR) and mineralocorticoid receptors (MR) are believed to classically bind DNA as homodimers or MR-GR heterodimers to influence gene regulation in response to pulsatile basal or stress-evoked glucocorticoid secretion. Pulsed corticosterone
John R Pooley +9 more
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Journal of Pharmacological Sciences, 2011 Mineralocorticoid receptor (MR) antagonists, such as spironolactone (SPI) and eplerenone (EPL), are useful for the treatment of hypertension and heart failure.
Tetsuro Nariai +5 more
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Brazilian Journal of Medical and Biological Research, 2007 Central angiotensin II (AngII) stimulates water and salt solution intake. Pretreatment with low-dose mineralocorticoid (DOCA) enhances this AngII-induced intake of salt solutions (the synergy theory) in Wistar and Sprague Dawley rats but not in Fischer ...
S.N. Thornton +2 more
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Steroid Receptors and Vertebrate Evolution
, 2019 Considering that life on earth evolved about 3.7 billion years ago, vertebrates are young, appearing in the fossil record during the Cambrian explosion about 542 to 515 million years ago.
Baker, Michael E.
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Effect of vasopressin 1b receptor blockade on the hypothalamic-pituitary-adrenal response of chronically stressed rats to a heterotypic stressor [PDF]
, 2009 Exposure to chronic restraint (CR) modifies the hypothalamic–pituitary–adrenal (HPA) axis response to subsequent acute stressors with adaptation of the response to a homotypic and sensitization of the response to a heterotypic stressor. Since vasopressin
Craighead, Mark +5 more
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Immune Effects of Corticosteroids in Sepsis
Frontiers in Immunology, 2018 Sepsis, a life-threatening organ dysfunction, results from a dysregulated host response to invading pathogens that may be characterized by overwhelming systemic inflammation or some sort of immune paralysis.
Nicholas Heming +6 more
doaj +1 more source
Hippocampal Memory Recovery After Acute Stress: A Behavioral, Morphological and Molecular Study [PDF]
, 2018 Indexación: Scopus.Laboratory of Neuroplasticity and Neurogenetics, Department of Biochemistry and Molecular Biology, Faculty of Chemistry and Pharmaceutical Sciences, Universidad de Chile, Santiago, Chile, 2Laboratorio Farmacología del Comportamiento ...
Ana M. Avalos +13 more
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Epidermal mineralocorticoid receptor plays beneficial and adverse effects in skin and mediates glucocorticoid responses [PDF]
, 2016 10 páginas, 6 figuras. Contiene material suplementarioGlucocorticoids (GCs) regulate skin homeostasis and combat cutaneous inflammatory diseases; however, adverse effects of chronic GC treatments limit their therapeutic use.
Boix, Julia +4 more
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Eplerenone reduces lymphangiogenesis in the contralateral kidneys of UUO rats
Scientific ReportsInflammation and fibrosis often occur in the kidney after acute injury, resulting in chronic kidney disease and consequent renal failure. Recent studies have indicated that lymphangiogenesis can drive renal inflammation and fibrosis in injured kidneys ...
Juan Hao +9 more
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Qué sabemos sobre las consecuencias a largo plazo de la separación materna temprana y la respuesta neuroendocrina al estrés [PDF]
, 2014 Adverse conditions during early life are a risk factor for stress-related diseases. How this early adversity induce long-term effects is not well understood, however there are several evidence that the stress hormones play a determining role.
Renard, Georgina Maria +1 more
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