Results 101 to 110 of about 2,343,081 (240)

Genomic and non-genomic effects of mineralocorticoid receptors and glucocorticoid receptors and their roles of pain modulation [PDF]

, 2018
Corticosteroids, including mineralocorticoids and glucocorticoids, are best known for their effective relief of inflammation and pain through activation of the intracellular mineralocorticoid (MR) and glucocorticoid receptors (GR) that changes gene ...
Li, Xiongjuan
core   +1 more source

Therapeutic potential of finerenone for diabetic cardiomyopathy: focus on the mechanisms

Diabetology & Metabolic Syndrome
Diabetic cardiomyopathy (DCM) is a kind of myocardial disease that occurs in diabetes patients and cannot be explained by hypertensive heart disease, coronary atherosclerotic heart disease and other heart diseases. Its pathogenesis may be closely related
Jing Wang, Haojie Xue, Jinyu He, Li Deng, Julong Tian, Yang Jiang, Jian Feng   +6 more
doaj   +1 more source

Hsp90 blockers inhibit adipocyte differentiation and fat mass accumulation.

PLoS ONE, 2014
Geldanamycin derivatives are benzoquinone ansamycin antibiotics that bind to Hsp90 and alter its function. The alteration of Hsp90 activity limits some cellular hormonal responses by inhibiting nuclear receptors activation. The nuclear receptors activity,
Sébastien Desarzens, Wan-Hui Liao, Caterina Mammi, Massimiliano Caprio, Nourdine Faresse   +4 more
doaj   +1 more source

Spironolactone treatment attenuates vascular dysfunction in type 2 diabetic mice by decreasing oxidative stress and restoring NO/GC signaling [PDF]

, 2015
Type 2 diabetes (DM2) increases the risk of cardiovascular disease. Aldosterone, which has pro-oxidative and pro-inflammatory effects in the cardiovascular system, is positively regulated in DM2.
Bruder-Nascimento, Thiago, Cau, Stefany B.A., Fais, Rafael S., Lopes, Rheure A.M., Mestriner, Fabiola L.A.C., Silva, Marcondes A.B., Tostes, Rita C., Touyz, Rhian M.   +7 more
core   +3 more sources

THE USE OF MINERALOCORTICOID RECEPTOR ANTAGONISTS IN THE PRE VENTION OF ATRIAL FIBRILLATION

Архивъ внутренней медицины, 2019
Atrial fibrillation (AF) is one of the most common cardiac rhythm disorders. Its prevalence is about 1 % in the general population and exceeds 7 % in individuals older than 60 years of age.
N. T. Vatutin, A. N. Shevelok, G. G. Taradin, I. N. Kravchenko   +3 more
doaj   +1 more source

Vascular endothelial mineralocorticoid receptors and epithelial sodium channels in metabolic syndrome and related cardiovascular disease. [PDF]

J Mol Endocrinol, 2023
Jia G, Hill MA, Sowers JR.
europepmc   +1 more source

Effects of Mineralocorticoid Receptors Blockade on FearMemory Reconsolidation in Rats

Basic and Clinical Neuroscience, 2011
Reconsolidation memory is defined as a process in which the retrieval of a previously consolidated memory returns to a labile state which is then subject to stabilization.
Ali Rashidy-Pour, Saeed Nikzad, Roghyeh Pakdel, Abbas Ali Vafaei   +3 more
doaj   +2 more sources

The expression of glucocorticoid and mineralocorticoid receptors in pituitary tumors causing Cushing's disease and silent corticotroph tumors. [PDF]

Front Endocrinol (Lausanne), 2023
Kober P, Rusetska N, Mossakowska BJ, Maksymowicz M, Pękul M, Zieliński G, Styk A, Kunicki J, Działach Ł, Witek P, Bujko M.   +10 more
europepmc   +1 more source

Hypertension: Renin-Angiotensin-Aldosterone System Alterations [PDF]

, 2015
Blockers of the renin-angiotensin-aldosterone system (RAAS), that is, renin inhibitors, angiotensin (Ang)-converting enzyme (ACE) inhibitors, Ang II type 1 receptor antagonists, and mineralocorticoid receptor antagonists, are a cornerstone in the ...
Danser, A.H.J. (Jan), Esch, J.H.M. (Joep) van, Meiracker, A.H. (Anton) van den, Riet, L. (Luuk) te, Roks, A.J.M. (Anton)   +4 more
core   +1 more source

Role of the Renin-Angiotensin System and Aldosterone on Cardiometabolic Syndrome

International Journal of Hypertension, 2011
Aldosterone facilitates cardiovascular damage by increasing blood pressure and through different mechanisms that are independent of its effects on blood pressure.
P. Stiefel, A. J. Vallejo-Vaz, S. García Morillo, J. Villar   +3 more
doaj   +1 more source