Results 181 to 190 of about 31,334 (301)

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP): A Comprehensive Review of Types, Pathophysiology, and Treatment Approaches

open access: yesBrain and Behavior, Volume 16, Issue 5, May 2026.
Chronic inflammatory demyelinating polyneuropathy is an autoimmune disorder causing demyelination, leading to distal weakness, sensory loss, and autonomic dysfunction. Immune activation triggers macrophage‐mediated myelin damage and conduction failure.
Ayesha Khan   +11 more
wiley   +1 more source

Dopamine‐Induced Seizure in a Heart Failure Patient: A Case Report and Review of Neurotoxic Implications

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT In heart failure patients, dopamine therapy, particularly at higher doses, may induce seizures due to its impact on cerebral blood flow and exacerbation of underlying hypoxemia and electrolyte imbalances. Close monitoring and cautious use of dopamine, with consideration of alternative inotropic agents like dobutamine, are essential to mitigate
Chuanwei Zhao   +4 more
wiley   +1 more source

Mineralocorticoid Receptors in Vascular Smooth Muscle: Blood Pressure and Beyond. [PDF]

open access: yesHypertension
Camarda ND   +3 more
europepmc   +1 more source

Cardiovascular‐Kidney‐Metabolic Syndrome in People With HIV: An Emerging Frontier for Clinical Pharmacology

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1136-1140, May 2026.
As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley   +1 more source

Corticosterone as a Physiological Biomarker: Decoding the Environment‐Cort‐Energy Paradigm

open access: yesEcology and Evolution, Volume 16, Issue 5, May 2026.
Corticosterone (cort) is increasingly used as a biomarker in wildlife conservation, though debate remains over which measures best capture physiological and environmental relationships. Using structural equation modeling on a 14‐year dataset, we evaluated the total hormone, free hormone, and CBG profile hypotheses linking cort, energetic state, and ...
B. Sunny Domschot   +4 more
wiley   +1 more source

Gut Dysbiosis as a Shared Mechanism in Obesity and Hypertension: Exploring a Promising Therapeutic Avenue

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 3, May 2026.
This review synthesises current knowledge on gut microbiome involvement in obesity and hypertension, evaluates microbiome‐based therapeutic strategies, and identifies critical research gaps to guide future investigations aimed at mitigating the dual pandemics.
Andrej Belančić   +7 more
wiley   +1 more source

Fasting and Caloric Restriction Activate an ADIOL‐NHR‐91‐Kynurenine Pathway Signaling Axis to Promote Healthspan

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
The steroid hormone ADIOL emerges as a key mediator of fasting–and caloric restriction–induced healthspan benefits in C. elegans. These regimens activate ADIOL production, which acts through the estrogen receptor β homolog NHR‐91 to reduce neural kynurenic acid levels and enhance healthspan independently of lifespan. ADIOL supplementation, even late in
Ana Guijarro‐Hernández   +6 more
wiley   +1 more source

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