Results 181 to 190 of about 31,334 (301)
Chronic inflammatory demyelinating polyneuropathy is an autoimmune disorder causing demyelination, leading to distal weakness, sensory loss, and autonomic dysfunction. Immune activation triggers macrophage‐mediated myelin damage and conduction failure.
Ayesha Khan +11 more
wiley +1 more source
Immunometabolic switch in hypertension: how dendritic cell mineralocorticoid receptors drive Th17 polarization and blood pressure control. [PDF]
Mikolajczyk TP, Śliwa T, Guzik TJ.
europepmc +1 more source
ABSTRACT In heart failure patients, dopamine therapy, particularly at higher doses, may induce seizures due to its impact on cerebral blood flow and exacerbation of underlying hypoxemia and electrolyte imbalances. Close monitoring and cautious use of dopamine, with consideration of alternative inotropic agents like dobutamine, are essential to mitigate
Chuanwei Zhao +4 more
wiley +1 more source
Mineralocorticoid Receptors in Vascular Smooth Muscle: Blood Pressure and Beyond. [PDF]
Camarda ND +3 more
europepmc +1 more source
As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley +1 more source
Corticosterone as a Physiological Biomarker: Decoding the Environment‐Cort‐Energy Paradigm
Corticosterone (cort) is increasingly used as a biomarker in wildlife conservation, though debate remains over which measures best capture physiological and environmental relationships. Using structural equation modeling on a 14‐year dataset, we evaluated the total hormone, free hormone, and CBG profile hypotheses linking cort, energetic state, and ...
B. Sunny Domschot +4 more
wiley +1 more source
This review synthesises current knowledge on gut microbiome involvement in obesity and hypertension, evaluates microbiome‐based therapeutic strategies, and identifies critical research gaps to guide future investigations aimed at mitigating the dual pandemics.
Andrej Belančić +7 more
wiley +1 more source
The steroid hormone ADIOL emerges as a key mediator of fasting–and caloric restriction–induced healthspan benefits in C. elegans. These regimens activate ADIOL production, which acts through the estrogen receptor β homolog NHR‐91 to reduce neural kynurenic acid levels and enhance healthspan independently of lifespan. ADIOL supplementation, even late in
Ana Guijarro‐Hernández +6 more
wiley +1 more source

