Mechanisms of Hepatitis B Virus cccDNA and Minichromosome Formation and HBV Gene Transcription [PDF]
VirusesHepatitis B virus (HBV) is the etiologic agent of chronic hepatitis B, which puts at least 300 million patients at risk of developing fibrosis, cirrhosis, and hepatocellular carcinoma.
Andoni Gómez-Moreno, Alexander Ploss
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Minichromosomes: Vectors for Crop Improvement [PDF]
Agronomy, 2015 Minichromosome technology has the potential to offer a number of possibilities for expanding current biofortification strategies. While conventional genome manipulations rely on random integration of one or a few genes, engineered minichromosomes would ...
Jon P. Cody +5 more
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BMC Cancer, 2019 Background Despite rising incidence rates of colorectal malignancies, only a few prognostic tools have been implemented in proven clinical routine. Cell division and proliferation play a significant role in malignancies.
A. Hendricks +11 more
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Heterologous Gene Expression in Chlamydomonas reinhardtii Chloroplast by Heterologous Promoters and Terminators, Intercistronic Expression Elements and Minichromosome [PDF]
Microbial BiotechnologyChlamydomonas reinhardtii, a model green alga for expressing foreign proteins, faces challenges in multigene expression and enhancing protein expression level in the chloroplast.
Yunling Guo +3 more
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Stable minichromosome and functional neocentromere derived from rye 7R chromosome arm [PDF]
BMC Plant BiologyBackground The study of newly formed centromere with stable transmission ability can provide theoretical guidance for the construction of artificial chromosomes. More neocentromeres are needed to study the mechanisms of their formation.
Zongxiang Tang +6 more
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Meiotic transmission of an in vitro-assembled autonomous maize minichromosome. [PDF]
PLoS Genetics, 2007 Autonomous chromosomes are generated in yeast (yeast artificial chromosomes) and human fibrosarcoma cells (human artificial chromosomes) by introducing purified DNA fragments that nucleate a kinetochore, replicate, and segregate to daughter cells.
Shawn R Carlson +8 more
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Parasites & Vectors, 2014 Background The genus Haematopinus contains 21 species of blood-sucking lice, parasitizing both even-toed ungulates (pigs, cattle, buffalo, antelopes, camels and deer) and odd-toed ungulates (horses, donkeys and zebras).
Simon D Song +2 more
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SMC5/6-Mediated Transcriptional Regulation of Hepatitis B Virus and Its Therapeutic Potential [PDF]
VirusesCells have developed various mechanisms to counteract viral infections. In an evolutionary arms race, cells mobilize cellular restriction factors to fight off viruses, targeted by viral factors to facilitate their own replication.
Johannes Bächer +2 more
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Expression of minichromosome maintenance genes in renal cell carcinoma
Cancer Management and Research, 2017 Hongbin Zhong,1,* Bin Chen,1,* Henrique Neves,2 Jinchun Xing,1 Youxin Ye,1 Ying Lin,1 Guohong Zhuang,3 Shu-Dong Zhang,4 Jiyi Huang,1,5 Hang Fai Kwok2 1Xiang’an Branch, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, People’
Zhong HB +9 more
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Drastic variation in mitochondrial genome organization between two congeneric species of bird lice (Philopteridae: Ibidoecus) [PDF]
BMC GenomicsThe over 4,100 species of bird lice are classified into 214 genera in the parvorders Amblycera and Ischnocera. Congeneric species of bird lice usually share much similarity in morphology and in mitochondrial (mt) genome organization.
Mei-Ling Cao +8 more
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