Results 11 to 20 of about 14,380 (242)

Columnar structure of SV40 minichromosome

AIMS Biophysics, 2015
Like the sequence of the strongest 601 clone nucleosome of Lowary and Widom, the SV40 genome sequence contains tracks of YR dinucleotides separated by small integers of the 10.4n base series (10, 11, 21 and 30 bases).
Edward N Trifonov
doaj   +2 more sources

Polyoma virus minichromosomes: associated DNA molecules [PDF]

Journal of Virology, 1981
Electron microscopy was used to identify and quantitate DNA molecules associated with 3H-labeled polyoma minichromosomes which had been fractionated on a sucrose gradient. The percentage of replicating DNA molecules observed in the fractions of the gradient normally designated the replicative intermediate region was up to ninefold higher than in ...
Marc R. Krauss, Robert M. Benbow
openalex   +4 more sources

Design of multi-epitope-based therapeutic vaccine candidates from HBc and HBx proteins of hepatitis B virus using reverse vaccinology and immunoinformatics approaches. [PDF]

PLoS ONE
The major problem in cases of chronic hepatitis B (CHB) is the failure of the patient's immune response to eliminate the covalently closed circular DNA (cccDNA) minichromosome of hepatitis B virus (HBV).
Patricia Gita Naully, Marselina Irasonia Tan, Husna Nugrahapraja, Aluicia Anita Artarini, Reza Aditama, Ernawati Arifin Giri-Rachman   +5 more
doaj   +2 more sources

Expression of minichromosome maintenance proteins in the exfoliated cells supplement sputum cytology in the diagnosis of lung cancer. [PDF]

Cytojournal
Panakkal N, Lekshmi A, Krishna KMJ, Saraswathy VV, Sujathan K.   +4 more
europepmc   +2 more sources

Sterility and structural variation in an arabidopsis pedigree carrying a ring minichromosome. [PDF]

Chromosome Res
Ordoñez B, Guo W, Chueakhunthod W, Henry IM, Comai L.   +4 more
europepmc   +3 more sources

Molecular insights into Spindlin1-HBx interplay and its impact on HBV transcription from cccDNA minichromosome

Nature Communications, 2023
Molecular interplay between host epigenetic factors and viral proteins constitutes an intriguing mechanism for sustaining hepatitis B virus (HBV) life cycle and its chronic infection.
Wei Liu, Qingjiang Yao, Xiaonan Su, Y. Deng, Mo Yang, Bo Peng, Fan Zhao, Chao-chao Du, Xiulan Zhang, Jinsong Zhu, Daliang Wang, Wenhui Li, Haitao Li   +12 more
semanticscholar   +1 more source

Precise Characterization and Tracking of Stably Inherited Artificial Minichromosomes Made by Telomere-Mediated Chromosome Truncation in Brassica napus

Frontiers in Plant Science, 2021
Plant artificial minichromosomes are the next-generation technology for plant genetic engineering and represent an independent platform for expressing foreign genes and the tools for studying the structure and function of chromosomes.
Xiangzhen Yin, Yingxin Zhang, Yingxin Zhang, Yuhong Chen, Jingqiao Wang, Richard R.-C. Wang, Chengming Fan, Zanmin Hu, Zanmin Hu   +8 more
doaj   +1 more source

SIRT7 restricts HBV transcription and replication through catalyzing desuccinylation of histone H3 associated with cccDNA minichromosome.

Clinical science, 2021
Chronic HBV infection is a significant public health burden worldwide. HBV cccDNA organized as a minichromosome in nucleus is responsible for viral persistence and is the key obstacle for a cure of chronic hepatitis B.
Hailing Yu, Sheng-tao Cheng, Fang Ren, Yong Chen, Xiao-feng Shi, V. Wong, B. Law, Ji-hua Ren, Shan Zhong, Wei-Xian Chen, Hong-mei Xu, Zhen-zhen Zhang, Jie-Li Hu, X. Cai, Yuan Hu, Wen‐lu Zhang, Quan-xin Long, Lin He, Zhong-Wen Hu, Hui Jiang, Hongzhong Zhou, A. Huang, Juan Chen   +22 more
semanticscholar   +1 more source

Plant minichromosomes [PDF]

Current Opinion in Biotechnology, 2016
Plant minichromosomes have the potential for stacking multiple traits on a separate entity from the remainder of the genome. Transgenes carried on an independent chromosome would facilitate conferring many new properties to plants and using minichromosomes as genetic tools.
James A, Birchler, Nathaniel D, Graham, Nathan C, Swyers, Jon P, Cody, Morgan E, McCaw   +4 more
openaire   +2 more sources

MCM4 is a novel prognostic biomarker and promotes cancer cell growth in glioma

Frontiers in Oncology, 2022
BackgroundGliomas account for 75% of all primary malignant brain tumors in adults and result in high mortality. Accumulated evidence has declared the minichromosome maintenance protein complex (MCM) gene family plays a critical role in modulating the ...
Shu Yang, Yixiao Yuan, Wenjun Ren, Haiyu Wang, Zhong Zhao, Heng Zhao, Qizhe Zhao, Xi Chen, Xiulin Jiang, Lei Zhang   +9 more
doaj   +1 more source