Results 131 to 140 of about 1,224,373 (238)

Altered Hippocampal Transcriptomic Profile Reveals Cognitive Impairment in Young Metabolically Obese, Normal‐Weight Rats, Prevented by Perinatal Leptin Intake

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 22, November 2025.
Early‐life exposure of rats to high‐fat‐isocaloric diet leads to metabolically obese, normal‐weight phenotype, and impaired cognition. Hippocampal transcriptomic analysis reveals disruption in pathways linked to obesity and cognitive decline, which is mitigated by perinatal leptin supplementation. PBMC share common altered genes with hippocampus, which
Carmen García‐Ruano   +3 more
wiley   +1 more source

Taxonomic revision of the genus Lactarius (Russulales, Basidiomycota) in Korea [PDF]

open access: yes, 2019
The genus Lactarius Pers. (Russulales) is a cosmopolitan group of Basidiomycota that forms ectomycorrhizal relationships primarily with both deciduous and coniferous trees.
Eimes, John   +5 more
core   +1 more source

Mapping the transcriptional landscape of algal resistance to viral infection reveals a core expression program

open access: yesNew Phytologist, Volume 248, Issue 3, Page 1368-1384, November 2025.
Summary Algal blooms and their demise by viruses drive global‐scale ecological processes in the ocean. These blooms form the foundation of marine food webs, regulate microbial communities, and shape biogeochemical cycles. Although algal populations are constantly infected by viruses, resistant subpopulations frequently emerge after the infection.
Talia S. Shaler   +5 more
wiley   +1 more source

Fluoride Stimulates the Proliferation of Osteoclasts in vitro by Upregulating MCM3 [PDF]

open access: yesInternational Journal Bioautomation, 2016
We have previously shown that the expression of the minichromosome maintenance protein 3 (MCM3) gene was upregulated in lymphocytes of patients with skeletal fluorosis.
Shengbin Bai   +6 more
doaj  

Site-specific DNA Mapping of Protein Binding Orientation Using Azidophenacyl Bromide (APB)

open access: yesBio-Protocol, 2020
The orientation of a DNA-binding protein bound on DNA is determinative in directing the assembly of other associated proteins in the complex for enzymatic action.
Himasha Perera, Michael Trakselis
doaj   +1 more source

Improved Screening for Anal Neoplasia by Immunocytochemical Detection of Minichromosome Maintenance Proteins [PDF]

open access: yesCancer Epidemiology, Biomarkers & Prevention, 2008
Abstract Purpose: Early detection of anal intraepithelial neoplasia (AIN) and anal squamous cell carcinoma (SCC) by screening will improve clinical outcome. Assessment of anal cytology samples using routine Papanicolaou testing suffers from shortcomings in sensitivity and/or specificity, suggesting that screening tests based on ...
Cinzia, Scarpini   +14 more
openaire   +2 more sources

Viral‐Directed Augmentation of Kupffer Cell Cross‐Presentation Provokes Antitumor Immunity Against Liver Metastasis

open access: yesAdvanced Science, Volume 12, Issue 39, October 20, 2025.
Targeting Kupffer cells (KC) with a single intravenous infusion of the oncolytic virus VSV‐M51R rather than VSV‐WT induces effective tumor regression in various types of liver metastatic cancers in mice. VSV‐M51R promotes KC proliferation and enhances their antigen cross‐presentation capacity without compromising viability, leading to the induction of ...
Chen Chen   +8 more
wiley   +1 more source

Role of the ubiquitin-selective CDC-48/UFD-1/NPL-4 chaperone in DNA replication [PDF]

open access: yes, 2012
Faithful transmission of genomic information requires tight spatiotemporal regulation of DNA replication factors. Posttranslational modifications, such as ubiquitylation, constitute a fast and effective mechanism to control such complex protein function.
Franz, André
core  

Effects of Differential Commercial Husbandry Conditions on the Tasmanian Atlantic Salmon Egg Transcriptome

open access: yesAquaculture, Fish and Fisheries, Volume 5, Issue 5, October 2025.
ABSTRACT Maternally inherited transcripts are crucial for the developmental competence of salmon embryos. Due to the wide variety of broodstock conditioning approaches used in commercial aquaculture, there is a need to understand how dynamic commercial environments impact the egg transcriptome and subsequent quality.
Xin Zhan   +4 more
wiley   +1 more source

Modulation of gene expression in endothelial cells in response to high LET nickel ion irradiation [PDF]

open access: yes, 2014
Ionizing radiation can elicit harmful effects on the cardiovascular system at high doses. Endothelial cells are critical targets in radiation-induced cardiovascular damage.
Aerts, An   +15 more
core   +1 more source

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