Results 161 to 170 of about 1,224,373 (238)

Rapid DNA replication origin licensing protects stem cell pluripotency

open access: yeseLife, 2017
Complete and robust human genome duplication requires loading minichromosome maintenance (MCM) helicase complexes at many DNA replication origins, an essential process termed origin licensing. Licensing is restricted to G1 phase of the cell cycle, but G1
Jacob Peter Matson   +10 more
doaj   +1 more source

Minichromosome Maintenance as a Genetic Assay for Defects in DNA Replication

open access: yesMethods, 1999
Minichromosome maintenance (mcm) is an effective genetic assay for mutants defective in DNA replication. Two classes of mcm mutants have been identified using this screen: those that differentially affect the activities of certain autonomously replicating sequences (ARSs) and those that uniformly affect the activities of all ARSs.
openaire   +3 more sources

Structure and regulatory role of the C-terminal winged helix domain of the archaeal minichromosome maintenance complex [PDF]

open access: gold, 2015
Christoph Wiedemann   +5 more
openalex   +1 more source

Position Effect Takes Precedence Over Target Sequence in Determination of Adenine Methylation Patterns in the Nuclear Genome of a Eukaryote, \u3cem\u3eTetrahymena thermophila\u3c/em\u3e [PDF]

open access: yes, 1998
Approximately 0.8% of the adenine residues in the macronuclear DNA of the ciliated protozoan Tetrahymena thermophila are modified to N6-methyladenine. DNA methylation is site specific and the pattern of methylation is constant between clonal cell lines ...
Karrer, Kathleen M.   +1 more
core   +1 more source

Highly Coordinated Gene Regulation in Mouse Skeletal Muscle Regeneration [PDF]

open access: yes, 2003
Mammalian skeletal muscles are capable of regeneration after injury. Quiescent satellite cells are activated to reenter the cell cycle and to differentiate for repair, recapitulating features of myogenesis during embryonic development.
Choi, Sangdun   +9 more
core   +1 more source

Risk model based on minichromosome maintenance 2 using objective assessment for predicting survival of neuroblastoma. [PDF]

open access: yesiScience, 2023
Zeng L   +9 more
europepmc   +1 more source

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