Results 221 to 230 of about 1,224,373 (238)

Zebrafish Minichromosome Maintenance Protein 5 Gene Regulates the Development and Migration of Facial Motor Neurons via Fibroblast Growth Factor Signaling

Developmental Neuroscience, 2021
Minichromosome maintenance protein 5 (MCM5), a member of the microchromosomal maintenance protein family, plays an important role in the initiation and extension of DNA replication.
Yongmei Wu, Sizhou Huang, Haixia Zhao, Kang Cao, Jinfan Gan, C. Yang, Zhen Xu, Shurong Li, B. Su   +8 more
semanticscholar   +1 more source

Hyperactivation of MEK/ERK pathway by Ca2+/calmodulin‐dependent protein kinase kinase 2 promotes cellular proliferation by activating cyclin‐dependent kinases and minichromosome maintenance protein in gastric cancer cells

Molecular Carcinogenesis, 2021
Although CAMKK2 is overexpressed in several cancers, its role and relevant downstream signaling pathways in gastric cancer (GC) are poorly understood. Treatment of AGS GC cells with a CAMKK2 inhibitor, STO‐609, resulted in decreased cell proliferation ...
M. A. Najar, Anjana Aravind, Shobha Dagamajalu, D. Sidransky, H. Ashktorab, D. Smoot, H. Gowda, T. Prasad, P. K. Modi, Aditi Chatterjee   +9 more
semanticscholar   +1 more source

Interaction of human minichromosome maintenance protein‐binding protein with minichromosome maintenance 2–7

The FEBS Journal, 2014
It has been reported that minichromosome maintenance protein‐binding protein (MCM‐BP) functions in the formation of the pre‐replication complex, unloading of minichromosome maintenance (MCM)2–7 from chromatin in late S phase, and formation of the cohesion complex by interacting with MCM3–7 proteins, suggesting that MCM‐BP functions in several different
Shunsuke, Kusunoki, Yukio, Ishimi
openaire   +2 more sources

Minichromosome maintenance proteins in cancer screening

European Journal of Cancer, 2009
Early detection of cancer leads to more effective treatment and improved patient survival. Many current cancer screening tests examine cells obtained from the surface of stratified epithelia, such as those of the cervix, urinary bladder, large bowel or airways.
Nicholas, Coleman, Ronald A, Laskey
openaire   +2 more sources

Expression of minichromosome maintenance proteins in Merkel cell carcinoma

Journal of the European Academy of Dermatology and Venereology, 2009
AbstractObjective  Minichromosome maintenance (MCM) nuclear proteins have barely been employed in the diagnosis of skin malignancies. We aimed to assess whether MCM immunohistochemistry can be utilized to examine tumour proliferation in Merkel cell carcinoma (MCC).Methods  In this pilot study, we studied skin specimens of eight patients with MCC.
T, Gambichler, A, Breininger, S, Rotterdam, P, Altmeyer, M, Stücker, A, Kreuter   +5 more
openaire   +2 more sources

Low doses of toxicants can enhance algae potential as biodiesel and biomass feedstocks

Renewable & Sustainable Energy Reviews, 2022
E. Agathokleous, J. Guo, Minichromosome Maintenance, Dna Primase, Subunit   +4 more
semanticscholar   +1 more source

Direct regulation of the minichromosome maintenance complex by MYCN in neuroblastoma

European Journal of Cancer, 2007
The c-Myc and MYCN oncogenes strongly induce cell proliferation. Although a limited series of cell cycle genes were found to be induced by the myc transcription factors, it is still unclear how they mediate the proliferative phenotype. We therefore analysed a neuroblastoma cell line with inducible MYCN expression.
Koppen, Arjen, Ait-Aissa, Rachida, Koster, Jan, van Sluis, Peter G., Ora, Ingrid, Caron, Huib N., Volckmann, Richard, Versteeg, Rogier, Valentijn, Linda J.   +8 more
openaire   +3 more sources

Metallothionein protein and minichromosome maintenance protein-2 expression in adrenocortical tumors

Annales d'Endocrinologie, 2019
Some resected adrenal-confined adrenocortical carcinomas metastasize and others not. The present study was designed to evaluate the expression of metallothionein protein (MT) and minichromosome maintenance protein-2 (MCM2) in adrenocortical carcinomas and adrenocortical adenomas, and to test the correlation between this and adrenocortical carcinoma ...
Leonard, Saiegh, Mohammad, Sheikh-Ahmad, Carmela, Shechner, Maria, Reut, Yusef, Darawsha, Sagit, Zolotov, Hila, Shefer, Ilan, Bejar, Jacob, Bejar   +8 more
openaire   +2 more sources

Immunohistochemical expression of minichromosome maintenance-3 protein in pleomorphic adenoma and mucoepidermoid carcinoma

Tanta Dental Journal, 2019
Introduction Salivary gland tumors represent a diverse set of tumors. Pleomorphic adenoma (PA) and mucoepidermoid carcinoma (MEC) are the most common benign and malignant salivary gland tumors respectively.
M. Arafa, A. Raghib, O. Wahba
semanticscholar   +1 more source

Minichromosome maintenance protein family member 6 mediates hepatocellular carcinoma progression by recruiting UBE3A to induce P53 ubiquitination.

International Journal of Biological Macromolecules, 2023
Xue Zhang, Saiyan Bian, Yao Ni, Linlin Zhou, Chenyu Yang, Chenfeng Zhang, Xieyin Sun, Nuo Xu, Shiyu Xu, Yilang Wang, Shudong Gu, Wenjie Zheng   +11 more
semanticscholar   +1 more source