Over expression of minichromosome maintenance genes is clinically correlated to cervical carcinogenesis. [PDF]
PLoS ONE, 2013 Minichromosome Maintenance (MCM) proteins play important roles in cell cycle progression by mediating DNA replication initiation and elongation. Among 10 MCM homologues MCM 2-7 form a hexamer and assemble to the pre-replication complex acting as ...
Mitali Das +7 more
doaj +3 more sources
Minichromosome Maintenance Complex (MCM) Genes Profiling and MCM2 Protein Expression in Cervical Cancer Development. [PDF]
Asian Pac J Cancer Prev, 2019 Objective: Minichromosome maintenance complex (MCM) proteins are essential for the process of DNA replication and cell division. This study aimed to evaluate MCM genes expression profiles and MCM2 protein in HPV-associated cervical carcinogenesis ...
Kaur G +4 more
europepmc +2 more sources
Prognostic significance of minichromosome maintenance mRNA expression in human lung adenocarcinoma. [PDF]
Oncol Rep, 2019 The minichromosome maintenance (MCM) gene family plays an essential role in DNA replication and cell cycle progression. However, MCM gene expression has not been well-studied in lung adenocarcinoma (LUAD). In the present study, the expression, prognostic
Li S, Jiang Z, Li Y, Xu Y.
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Expression of minichromosome maintenance genes in renal cell carcinoma [PDF]
Cancer Management and Research, 2017 Hongbin Zhong,1,* Bin Chen,1,* Henrique Neves,2 Jinchun Xing,1 Youxin Ye,1 Ying Lin,1 Guohong Zhuang,3 Shu-Dong Zhang,4 Jiyi Huang,1,5 Hang Fai Kwok2 1Xiang’an Branch, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, People’
Zhong HB +9 more
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Genome-wide investigation of the clinical significance and prospective molecular mechanism of minichromosome maintenance protein family genes in patients with Lung Adenocarcinoma. [PDF]
PLoS One, 2019 Our current study is to identify clinical significance of minichromosome maintenance (MCM) gene expression in Lung Adenocarcinoma (LUAD) using genome-wide RNA sequencing (RNA-seq) dataset and bioinformatics analysis tools.
Liu K, Kang M, Liao X, Wang R.
europepmc +2 more sources
Expression of Minichromosome Maintenance Proteins (MCM) and Cancer Prognosis: A meta-analysis. [PDF]
J Cancer, 2018 Minichromosome maintenance proteins (MCM) played a critical role in replication and cell cycle progression. However, their prognostic roles in cancer remain controversial.
Gou K +5 more
europepmc +2 more sources
A Direct Interaction Between P53-Binding Protein 1 and Minichromosome Maintenance Complex in Hepg2 Cells [PDF]
Cellular Physiology and Biochemistry, 2018 Background/Aims: Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths worldwide. DNA damage repair in cancer cells is a promising approach for the treatment of cancers.
Yong Chen +4 more
doaj +2 more sources
Expression of minichromosome maintenance protein 2 as a marker for proliferation and prognosis in diffuse large B-cell lymphoma: a tissue microarray and clinico-pathological analysis [PDF]
BMC Cancer, 2005 Background Minichromosome maintenance (MCM) proteins are essential for the initiation of DNA replication and have been found to be relevant markers for prognosis in a variety of tumours.
Wild Peter J +7 more
doaj +2 more sources
Cedrol, a Sesquiterpene Isolated from Juniperus chinensis, Inhibits Human Colorectal Tumor Growth associated through Downregulation of Minichromosome Maintenance Proteins. [PDF]
J Cancer Prev, 2022 Jin S +7 more
europepmc +3 more sources
Expression of minichromosome maintenance proteins in the exfoliated cells supplement sputum cytology in the diagnosis of lung cancer. [PDF]
CytojournalPanakkal N +4 more
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