Expression of Minichromosome Maintenance Protein 2 (MCM2) in Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma: A Systematic Review. [PDF]
Ahire MS +4 more
europepmc +3 more sources
MCM4 is a novel prognostic biomarker and promotes cancer cell growth in glioma
BackgroundGliomas account for 75% of all primary malignant brain tumors in adults and result in high mortality. Accumulated evidence has declared the minichromosome maintenance protein complex (MCM) gene family plays a critical role in modulating the ...
Shu Yang +9 more
doaj +1 more source
Molecular functions of MCM8 and MCM9 and their associated pathologies
Summary: Minichromosome Maintenance 8 Homologous Recombination Repair Factor (MCM8) and Minichromosome Maintenance 9 Homologous Recombination Repair Factor (MCM9) are recently discovered minichromosome maintenance proteins and are implicated in multiple ...
Noah Cornelis Helderman +9 more
doaj +1 more source
Determinants of RPA megafoci localization to the nuclear periphery in response to replication stress
Upon replication stress, ssDNA, coated by the ssDNA-binding protein RPA, accumulates and generates a signal to activate the replication stress response. Severe replication stress induced by the loss of minichromosome maintenance helicase subunit Mcm4 in ...
Seong Min Kim, Susan L Forsburg
doaj +1 more source
Minichromosome maintenance protein 10 (MCM10) is critical for eukaryotic DNA replication. Here, by modelling MCM10 variants in human cell lines, the authors reveal a mechanism of MCM10-associated disease, finding that loss of MCM10 function constrains ...
Ryan M. Baxley +25 more
doaj +1 more source
Interaction of HTLV-1 Tax with minichromosome maintenance proteins accelerates the replication timing program [PDF]
Willems Luc +4 more
doaj +2 more sources
Cohesin interaction with centromeric minichromosomes shows a multi-complex rod-shaped structure. [PDF]
Cohesin is the protein complex responsible for maintaining sister chromatid cohesion. Cohesin interacts with centromeres and specific loci along chromosome arms known as Chromosome Attachment Regions (CARs). The cohesin holocomplex contains four subunits.
Alexandra Surcel +3 more
doaj +1 more source
Expression of gamma-aminobutyric acid type A receptor subunit π and minichromosome maintenance-3 in breast cancer patients treated with neoadjuvant chemotherapy: a target molecule or a proliferation marker? [PDF]
İriagac Y +6 more
europepmc +2 more sources
Inflammatory responses in primary muscle cell cultures in Atlantic salmon (Salmo salar) [PDF]
Peer reviewedPublisher ...
Martin, Samuel A.M. +3 more
core +2 more sources
Minichromosome maintenance proteins (MCMs) are considered to be essential factors coupling DNA replication to both cell cycle progression and checkpoint regulation. Previous studies have shown that dysregulation of MCMs are implicated in tumorigenesis of
Chen Huang +6 more
doaj +1 more source

