Results 51 to 60 of about 1,205,791 (198)

The enzymes LSD1 and Set1A cooperate with the viral protein HBx to establish an active hepatitis B viral chromatin state [PDF]

, 2016
Indexación: Web of ScienceWith about 350 million people chronically infected around the world hepatitis B is a major health problem. Template for progeny HBV synthesis is the viral genome, organized as a minichromosome (cccDNA) inside the hepatocyte ...
Alarcon, V, Alvarez, F, De Ferrari, GV, Flores, Y, Hernandez, S, Kann, M, Loyola, A, Rubio, L, Varas-Godoy, M, Villanueva, RA   +9 more
core   +2 more sources

Expression of Mcm2, geminin and Ki67 in normal oral mucosa, oral epithelial dysplasias and their corresponding squamous-cell carcinomas [PDF]

, 2009
Proteins necessary for the normal regulation of the cell cycle include minichromosome maintenance protein 2 (Mcm2) and geminin. These are overexpressed in several premalignant and malignant tumours.
A Freeman, A Ibarra, A Quaglia, A Shetty, A Torres-Rendon, EM Diaz Jr, G T Craig, G Xouri, GH Williams, GH Williams, I Kodani, I Kodani, IS Scott, IT Todorov, J Gerdes, J Mork, JA Wohlschlegel, JJ Going, K Stoeber, KK Tachibana, KL Eward, L Barnes, MA Gonzalez, MR Alison, MV Meng, NC Lea, P Chatrath, P M Speight, S Roy, SB Wharton, SB Wharton, SE Kearsey, SR Kingsbury, SS Napier, T Takeda, TJ Dudderidge, TJ McGarry   +36 more
core   +2 more sources

Diagnosis of pancreaticobiliary malignancy by detection of minichromosome maintenance protein 5 in biliary brush cytology [PDF]

, 2017
Background: Biliary brush cytology is the standard method of evaluating biliary strictures, but is insensitive at detecting malignancy. In pancreaticobiliary cancer minichromosome maintenance replication proteins (MCM 2–7) are dysregulated in the ...
Chapman, MH, Huggett, MT, Johnson, GJ, Keane, MG, Mackay, J, Pereira, SP, Thorburn, D, Webster, GJ   +7 more
core   +1 more source

Microarray analysis of canine papillomavirus lesions [PDF]

, 2013
Papillomaviren verursachen eine breite Palette von Krankheitsbildern bei Mensch und Tier, welche von asymptomatischen Infektionen, gutartigen Warzen, pigmentierten Plaques, in situ Karzinomen bis zu invasiven Plattenepithelkarzinomen reichen.
Vetsch, Elisabeth
core   +1 more source

Minichromosome Maintenance Expression Defines Slow-Growing Gastroenteropancreatic Neuroendocrine Neoplasms

Translational Oncology, 2016
BACKGROUND: Small intestinal neuroendocrine neoplasm (SI-NEN) proliferation is quantified by Ki67 measurements which capture G1-G2M phases of the cell cycle.
Simon Schimmack, Ben Lawrence, Barton Kenney, Hubertus Schmitz-Winnenthal, Irvin M. Modlin, Mark Kidd   +5 more
doaj   +1 more source

Double-strand break repair and homologous recombination in Schizosaccharomyces pombe [PDF]

, 2006
In recent years our understanding of double strand break repair and homologous recombination in Schizosaccharomyces pombe has increased significantly, and the identification of novel pathways and genes with homologues in higher eukaryotes has increased ...
Ahmad, Ahmad, Ahn, Ahnesorg, Akamatsu, Assenmacher, Baumann, Boddy, Boddy, Bonatto, Bransteitter, Buck, Callebaut, Caspari, Catlett, Cervantes, Chahwan, Cheok, Connelly, Cooper, Doe, Doe, Doe, Doe, Dudasova, Farah, Farah, Ferreira, Ferreira, Fukushima, Gaillard, Goedecke, Goodwin, Grishchuk, Haber, Hartsuiker, Hefferin, Jang, Jung, Khasanov, Khasanov, Kibe, Kim, Kim, Krogh, Lambert, Laursen, Macris, Maftahi, Maftahi, Manolis, Marchetti, Martin, McGlynn, Moore, Morishita, Muris, Muris, Muris, Murray, Nakada, Nakamura, Oakley, Ono, Osman, Osman, Osman, Ostermann, Paques, Parker, Prudden, Sauvageau, Schmidt, Segurado, Shinohara, Smith, Steiner, Stewart, Sung, Suto, Szankasi, Szostak, Tarsounas, Tavassoli, Thacker, Tomita, Tomita, Tsutsui, Tsutsui, Ueno, van den Bosch, van den Bosch, Virgin, Virgin, Wang, Weterings, Whitby, Whitby, Wilson, Win, Win, You, Young   +102 more
core   +2 more sources

METTL3 Promotes the Progression of Gastric Cancer via Targeting the MYC Pathway

Frontiers in Oncology, 2020
Methyltransferase-like 3 (METTL3), a major component of the N6-methyladenosine (m6A) methyltransferase complex, has been suggested to function as an oncogene in several cancers.
Dong-Dong Yang, Dong-Dong Yang, Zhan-Hong Chen, Zhan-Hong Chen, Kai Yu, Jia-Huan Lu, Qi-Nian Wu, Yun Wang, Huai-Qiang Ju, Rui-Hua Xu, Ze-Xian Liu, Zhao-Lei Zeng   +11 more
doaj   +1 more source

cccDNA Surrogate MC-HBV–Based Screen Identifies Cohesin Complex as a Novel HBV Restriction FactorSummary

Cellular and Molecular Gastroenterology and Hepatology, 2022
Background & Aims: Covalently closed circular DNA (cccDNA) of hepatitis B virus (HBV), existing as a stable minichromosome in the hepatocyte, is responsible for persistent HBV infection.
Zhuanchang Wu, Liyuan Wang, Xin Wang, Yang Sun, Haoran Li, Zhaoying Zhang, Caiyue Ren, Xiaohui Zhang, Shuangjie Li, Jinghui Lu, Leiqi Xu, Xuetian Yue, Yue Hong, Qiang Li, Haizhen Zhu, Yaoqin Gong, Chengjiang Gao, Huili Hu, Lifen Gao, Xiaohong Liang, Chunhong Ma   +20 more
doaj   +1 more source

Ciz1 cooperates with cyclin-A-CDK2 to activate mammalian DNA replication in vitro [PDF]

, 2010
Initiation of mammalian DNA replication can be reconstituted from isolated G1-phase nuclei and cell extracts, supplemented with cyclin-dependent protein kinases (CDKs).
Ainscough, Berezney, Brown, Cardoso, Chevalier, Cook, Coverley, Coverley, den Hollander, Dijkwel, Djeliova, Fujita, Furstenthal, Geng, Geng, Harper, Hozak, Krude, Lowe, Mailand, Mitsui, Moore, Parisi, Radichev, Sherr, Stoeber, Su, Takeda, Tatsumi, Wilmes, Wohlschlegel   +30 more
core   +3 more sources

Identification, validation, and targeting of the mutant p53-PARP-MCM chromatin axis in triple negative breast cancer

npj Breast Cancer, 2017
Personalized medicine: Mutated tumors respond to therapy Mutations in the p53 tumor suppressor gene could offer a predictive biomarker of response to certain drugs in triple-negative breast cancer.
Wei-Gang Qiu, Alla Polotskaia, Gu Xiao, Lia Di, Yuhan Zhao, Wenwei Hu, John Philip, Ronald C. Hendrickson, Jill Bargonetti   +8 more
doaj   +1 more source