Results 121 to 130 of about 3,346,804 (300)

Square-Root Balancing and Computation of Minimal Realizations of Periodic Systems [PDF]

open access: yes, 1998
We propose a numerically reliable approach for balancing and minimal realization of linear periodic systems with time-varying dimensions. The proposed approach to balancing belongs to the family of square-root methods with guaranteed enhanced ...
Varga, A.
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Restorative treatment decisions for carious lesions: Do Russian dentists and dental students apply minimal intervention dentistry? [PDF]

open access: yesBMC Oral Health, 2021
Drachev SN   +9 more
europepmc   +1 more source

Minimal invasive dental treatment options

open access: yes, 2017
There is no doubt that dentistry is evolving. New methods and new ideas are emerging and this is what MID is all about. Current idea of MID stands on "constriction with conviction" and its early detection, reducing cariogenic flora, minimal intervention ...
Lee, Hyunjae
core  

Minimal Intervention in Pediatric Dentistry [PDF]

open access: yes, 1970
Dental caries is an infectious disease, identifying the risk factors and controlling them is important in preventing tooth demineralization. Early recognition of risk factors allows dentistto implement preventive regimes.
Gunda, Sachin, Varma, Narendra
core  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Balancing related methods for minimal realization of periodic systems [PDF]

open access: yes, 1999
We propose balancing related numerically reliable methods to compute minimal realizations of linear periodic systems with time-varying dimensions. The first method belongs to the family of square-root methods with guaranteed enhanced computational ...
Varga, A.
core  

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