Results 141 to 150 of about 1,148,447 (292)
Frequent sweetened beverage consumption is associated with accelerated biological aging in a large Chinese population. Five gut microbial genera are consistently enriched in both frequent sweetened beverage consumers and individuals with accelerated aging and show significant mediating effects, suggesting a potential microbiota‐related pathway linking ...
Yuwei Shi +14 more
wiley +1 more source
Degree bounds of minimal polynomials and polynomial automorphisms
Let \(k\) be a field, \(h_ 1,\dots, h_ n\in k[x_ 1,\dots, x_{n-1}]=: k^{[n-1]}\) contain \(n-1\) algebraically independent polynomials. The author has shown earlier, that there exists, up to a non-zero constant factor, a unique irreducible polynomial \(m\) in \(n\) variables such that \(m(h_ 1, \dots,h_ n)=0\), called the minimal polynomial of \(h_ 1 ...
openaire +3 more sources
A polynomial algebraic approach to Lyapunov stability analysis of higher-order 2D systems
We introduce a four-variable polynomial matrix equation which plays an essential role in the stability analysis of discrete 2-D systems and in the computation of Lyapunov functions for such systems; we call this the 2-D polynomial Lyapunov equation (2-D ...
Kojima, Chiaki +2 more
core +1 more source
A Generative Neuro‐Symbolic AI for Protein Sequence Design
We introduce EffieDes, a neuro‐symbolic framework coupling deep learning‐based fitness landscape parameterization with exact automated reasoning. Unlike greedy sampling, EffieDes identifies sequences that globally optimize fitness while satisfying intricate design constraints.
Marianne Defresne +12 more
wiley +1 more source
To accelerate the inverse design of heterostructured metal matrix composites, a closed‐loop scientific machine learning framework integrates continual learning prediction with NSGA‐II‐PMCP optimization. The framework maps microstructural descriptors to strength, toughness, and modulus, expands high‐quality Pareto solutions, and guides experimentally ...
Zhiyan Zhong +11 more
wiley +1 more source
Automation and Active Learning for the Multi‐Objective Optimization of Antibody Formulations
Successful antibody formulation necessitates balancing factors such as thermal stability, colloidal stability, and viscosity across a vast excipient design space. This work integrates robotic liquid handling, high‐throughput biophysical characterization, and multi‐objective Bayesian optimization in an iterative closed‐loop Design‐Build‐Test‐Learn cycle.
D. Christopher Radford +3 more
wiley +1 more source
A Unifying Thermodynamic Model for Phase Separation and Aging of Biopolymers
Phase separation and aging of intrinsically disordered proteins are placed in a unifying framework. A thermodynamically consistent time‐dependent version of associating‐polymer theory shows how the processes are intricately coupled. Assuming aging to occur through interacting sites resulting from reversible conformational transitions, the model ...
Jasper J. Michels +2 more
wiley +1 more source
A soft hybrid multi‐wavelength PPG wearable acquires neonatal signals. Synchronized PPG and invasive ABP data are segmented into fixed windows. A 1D‐EfficientNet model predicts segment‐level SBP and DBP. Model performance is examined with retrospective subgroup analysis across acquisition conditions.
Wenqi Shi +12 more
wiley +1 more source
Single‐Atom‐Enhanced Fully Inkjet‐Printed Electrochemical Sensor for Dopamine Detection
Fully inkjet‐printed paper‐based dopamine sensors are fabricated using nitrogen‐doped graphene acid functionalized with copper single atoms. The copper sites uniquely enhance dopamine oxidation through strong molecular adsorption, as verified by electrochemical measurements and DFT calculations. The approach highlights the potential of single‐atom inks
Martin‐Alex Nalepa +11 more
wiley +1 more source
The representations, including polynomial, of functions over final fields have been actively investigated. The complexity of such representations is the main stream of research.
A. Baliuk, A.S. Zinchenko
doaj

