Results 51 to 60 of about 768,787 (306)

Minimal surfaces

, 2021
[en] In the present work we define the concept of Minimal Surface and prove some important results related to it. To begin with, we review some elementary definitions and results of differential geometry. Then, we study normal variations of curves and surfaces and solve some optimisation problems as examples of this techniques.
openaire   +3 more sources

Minimal surfaces in AdS C-metric

Physics Letters B, 2017
We shed some light on the field theory interpretation of C-metric by investigating the minimal surfaces which are homologous to the given boundary regions. The accelerating black holes change the asymptotic structure of the space–time.
Hao Xu
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Analysis of the Surface Quality Characteristics in Hard Turning Under a Minimal Cutting Fluid Environment

Applied Mechanics
This paper analyzes the surface quality characteristics, such as arithmetic average roughness (Ra), maximum peak-to-valley height (Rt), and average peak-to-valley height (Rz), in hard turning of AISI 52100 steel using a (TiN/TiCN/Al2O3) coated carbide ...
Sandip Mane, Rajkumar Bhimgonda Patil, Anindita Roy, Pritesh Shah, Ravi Sekhar   +4 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Surfaces of Minimal Capacity

Proceedings of the National Academy of Sciences, 1940
Not ...
openaire   +4 more sources

Metric-minimizing surfaces revisited [PDF]

Geometry & Topology, 2019
A surface which does not admit a length nonincreasing deformation is called metric minimizing. We show that metric minimizing surfaces in CAT(0) spaces are locally CAT(0) with respect to their intrinsic metric.
Petrunin, Anton, Stadler, Stephan
openaire   +3 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The robotic future of minimally invasive cytoreduction and hyperthermic intraperitoneal chemotherapy for peritoneal surface malignancies [PDF]

, 2023
Joanna Ortega, Theofano Orfanelli, Edward A. Levine, Ioannis T. Konstantinidis   +3 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source