Results 141 to 150 of about 224,088 (359)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Checking Mechanism in Modern Persian: A Minimalist Analysis of Case and Theta Marking [PDF]

open access: yesمطالعات زبان‌‌ها و گویش‌های غرب ایران, 2013
This study reviews and analyzes checking system in modern Persian according to Case and Theta features in Minimalist approach. In this study which is done by analytical-descriptive methods, the way structural cases such as Nominative, Accusative, Dative,
Arsalan Golfam, Maryam Najimi
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Minimalismo: a vueltas con el concepto de un(as) arte(s), reflexiones en torno al ciclo ¿los límites de la composición?

open access: yesBajo Palabra, 2016
La primera parte de este texto critica la intervención teórica de Michael Nyman sobre las nociones de “Minimalismo” y “música experimental”, señalando ciertas confusiones habituales.
David Díaz Soto
doaj  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

The roots of syntax and how they grow: Organic Grammar, the Basic Variety and Processability Theory. [PDF]

open access: yes, 2005
This is a pre-publication version of Vainikka, A. and M. Young-Scholten. 2005. The roots of syntax and how they grow: Organic Grammar, the Basic Variety and Processability Theory. In S. Unsworth, T. Parodi, A. Sorace and M.
Vainikka, Anne Marjatta
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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