Results 141 to 150 of about 11,183 (286)

Minimalism

open access: yes, 2019
Minimalism means living with intentionality. It is a mindset to remove the excesses of life and focus on what is truly important (Nicodemus 2015). Minimalism encourages people to let go of material goods that do not serve a purpose or bring joy to their ...
Ledder, Lindsay
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

A Guide to Digital Decluttering: A Review of Digital Minimalism [PDF]

open access: yes, 2019
Digital minimalism is not Luddism, which rejects the technological innovations of the day. Instead, it rejects the way in which most people engage these innovations.
Janssen, Mike
core  

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Minimalism and the abstract

open access: yes, 2004
Minimalism and the ...
M Takolander (14536601)
core  

Variation, evolution and the syntax of Afro-Bolivian Spanish gender agreement

open access: yesJournal of Ibero-Romance Creoles, 2010
This paper combines sociolinguistic and formal syntactic approaches to characterize the constraints regulating gender agreement variation across the Determiner Phrase (DP) in Afro-Bolivian Spanish (ABS).
Sandro Sessarego   +1 more
doaj  

On Minimal and Almost-Minimal Systems of Notations [PDF]

open access: yesTransactions of the American Mathematical Society, 1965
Luckham, D., Putnam, H.
openaire   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

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