Results 131 to 140 of about 1,080,179 (309)

Tailoring minimally invasive gynaecological surgery based on biogenomic findings

open access: yes, 2007
Tailoring minimally invasive gynaecological surgery can be defined as the pre-emptive prophylactic operative removal of a reproductive organ or a part of it, based on molecular genetic analysis, prior to malignant transformation or when the cancer is in ...
Leo G   +7 more
core  

The Miami International Evidence-based Guidelines on Minimally Invasive Pancreas Resection

open access: yes, 2020
Objective: The aim of this study was to develop and externally validate the first evidence-based guidelines on minimally invasive pancreas resection (MIPR) before and during the International Evidence-based Guidelines on Minimally Invasive Pancreas ...
International Study Group on Minimally Invasive Pancreas Surgery (I-MIPS)
core  

Multi-omics analysis of copper metabolism-related molecular subtypes and risk stratification for osteosarcoma

open access: yesDiscover Oncology
Background As the most common primary malignant bone tumor, further investigation into risk stratification for osteosarcoma (OS) prognosis is of significant clinical importance.
Yang Zhang   +7 more
doaj   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

Clinical application of arthroscopy-assisted minimally invasive therapy in Chinese elderly with type III Pilon fracture

open access: yes, 2017
Peiming Liu, Yong Guo, Ying Wen, Wei Wang The Eleventh Department of Orthopaedics, The Fifth Hospital of Harbin, Harbin, China Objective: Pilon fracture is so complex that its therapy poses a great challenge to surgeons.
Wen Y, Guo Y, Liu P, Wang W
core  

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay   +15 more
wiley   +1 more source

Stem cell therapy-based approaches in experimental endometriosis: a systematic review

open access: yesReproductive Biology and Endocrinology
Background Stem cell-based therapies have emerged as a promising approach for endometriosis due to their regenerative and immunomodulatory properties. Although numerous preclinical studies have reported beneficial effects, no systematic synthesis has yet
Isabel Suárez-Carrasco   +5 more
doaj   +1 more source

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab   +19 more
wiley   +1 more source

Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph   +5 more
wiley   +1 more source

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