Results 71 to 80 of about 133,022 (296)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Facial Rejuvenation Enhancing Cheek Lift

Archives of Plastic Surgery, 2017
Supported by recent literature on the signs of aging of the middle and lower face, our clinical research has documented a loss of volume of the deep structural components of the central face and a progressive descent of the nasolabial fat and the jowl ...
Philippe Bellity, Jonathan Bellity
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Minimally invasive valve surgery including patients of combined simultaneous surgery: a retrospective study

Journal of Cardiothoracic Surgery, 2023
Objective This study investigated the perioperative safety and advantages of performing a minimally invasive valve surgery (MIVS) and conducting a preliminary examination of the combined simultaneous surgery (CSS).
Yun Ling, Huaxin Chen, Pengxiong Zhu, Tian Li, Bangde Xue, Jun Liu   +5 more
doaj   +1 more source

Minimally invasive management of central ECMO after ascending aortic surgery

, 2019
A small percentage of ascending aortic surgical procedures require temporary mechanical circulatory support, of which veno-arterial extracorporeal membrane oxygenation (V-A ECMO) is the most established technique.
Bidar, Elham, Natour, Ehsan, Heuts, Samuel, Lorusso, Roberto   +3 more
core   +1 more source

Comparing Minimally Invasive Vs. Traditional Surgical Techniques In Facial Rejuvenation

, 2023
Background: Facial aging shows three main features which include loose skin, decreased volume appearance and developing wrinkles. Medical professionals have established both surgical procedures and non-surgical interventions to treat facial aging ...
Muhammad Shadman, Syed Mohammad Haider, Amir Taimur Khan, Sadaf Imran, Hamza Khan Shahbazi
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Sequelae and Surgical Management of Giant Cardiac Myxoma [PDF]

Texas Heart Institute Journal
Cardiac myxomas are a rare phenomenon within the general population, and although there are reports of them, giant myxomas are not common in the medical literature. This report presents a case of a giant left atrial cardiac myxoma in a 57-year-old female
Norvin Hernandez, BS, Michael DiLeo, BSA, Christopher K. Wong, MD, MSc, Mahboob Alam, MD   +3 more
doaj   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Clinical Assessment of Open Flap Debridement Using Magnifying Loupes and Surgical Operating Microscope: A Split-Mouth Randomized Controlled Clinical Trial

Frontiers in Dentistry
Objectives: To overcome the drawbacks of the conventional flap surgery, newer surgical techniques like minimally invasive surgery were evolved to optimize the primary closure of the flap.
Jaswitha Vintha, Mohan Kumar Pasupuleti, Gautami Subhadra Penmetsa, Sruthima Naga Venkata Satya Gottumukkala, Ramesh Santosh Venkata Konathala, Santosh Vamsi Eagala   +5 more
doaj   +1 more source