Results 81 to 90 of about 3,373,836 (300)

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Clinical Assessment of Open Flap Debridement Using Magnifying Loupes and Surgical Operating Microscope: A Split-Mouth Randomized Controlled Clinical Trial

Frontiers in Dentistry
Objectives: To overcome the drawbacks of the conventional flap surgery, newer surgical techniques like minimally invasive surgery were evolved to optimize the primary closure of the flap.
Jaswitha Vintha, Mohan Kumar Pasupuleti, Gautami Subhadra Penmetsa, Sruthima Naga Venkata Satya Gottumukkala, Ramesh Santosh Venkata Konathala, Santosh Vamsi Eagala   +5 more
doaj   +1 more source

SHORT-TERM CLINICAL OUTCOMES OF AWAKE AND OUTPATIENT TRANSFORAMINAL ENDOSCOPIC LUMBAR FORAMINOTOMY AND INTERSPINOUS SPACER DEVICE [PDF]

Coluna/Columna
Objective: To evaluate the clinical outcomes achieved with the combined surgical management of Transforaminal Endoscopic Lumbar Foraminoplasty (TELF) with an Interspinous Spacer Device (ISD) in patients with DS grades I and II and LSS.
Jorge Felipe Ramírez León, Yetzalis Antonieta Fernández Vera, Carolina Ramírez Martínez, José Gabriel Rugeles Ortíz, Nicolás Prada Ramírez, Viviana Marcela Plazas Bedoya, João Paulo Machado Bergamaschi, Gabriel Oswaldo Alonso Cuéllar   +7 more
doaj   +2 more sources

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Minimally invasive procedures

, 2015
Minimally invasive procedures, which include laparoscopic surgery, use state-of-the-art technology to reduce the damage to human tissue when performing surgery.
Mpoukovinas, I., Papaiwannou, A., Karavergou, A., Zissimopoulos, A., Trakada, G., Michail, C., Zarogoulidis, P., Pitsiou, G., Zarogoulidis, K., Baka, S., Tsakiridis, K., Anagnostopoulos, D., Rapti, A., Karavasilis, V., Lazaridis, G., Lampaki, S., Baltayiannis, N., Kioumis, I., Katsikogiannis, N.   +18 more
core   +1 more source

ADAMKIEWICZ’S ARTERY IN ENDOSCOPIC SURGERY: NARRATIVE REVIEW [PDF]

Coluna/Columna
Endoscopic spine surgery has become increasingly popular among specialized surgeons, driven by its minimally invasive approach and increasing clinical versatility.
Renan Herbert Ferreira, Daniel Ferreira Ghedini, Cleanto Moreira de Lacerda, Thiago Queiroz Soares, Ariel Falbel Lugão, Álvaro Dowling Montalva, Sonja Ellen Lobo, João Paulo Machado Bergamaschi   +7 more
doaj   +2 more sources

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Minimally invasive cardiac surgical procedures in female population

Journal-Cardiovascular Surgery, 2014
With the development of minimally invasive cardiac surgical procedures in recent years, many minimal incisions have been used to perform operations on patients with heart diseases. In this study, we documented our experience with limited skin incisions for congenital heart diseases, pericardial disease and cardiac tumors.
Ferit Cicekoglu, Seyhan Babaroglu, Onur Hanedan, Murat Songur, Garip Altintas, Kerem Yay   +5 more
openaire   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source