An Improved Bayesian Pick-the-Winner (IBPW) Design for Randomized Phase II Clinical Trials. [PDF]
ABSTRACT Phase II clinical trials play a pivotal role in drug development by screening a large number of drug candidates to identify those with promising preliminary efficacy for phase III testing. Trial designs that enable efficient decision‐making with small sample sizes and early futility stopping while controlling for type I and type II errors in ...
Lei W, Peng M, Altorki N, Kathy Zhou X.
europepmc +2 more sources
Exact Randomized Two-Stage Phase 2 Clinical Trial Designs for Two Binary Co-Primary Endpoints. [PDF]
ABSTRACT Phase 2 clinical trials typically rely on a single primary endpoint, yet in many settings, treatment efficacy must be demonstrated across multiple co‐primary endpoints. Such settings require intersection‐union hypothesis testing, in which the global null hypothesis is rejected only when all individual component hypotheses are rejected ...
Jung H +3 more
europepmc +2 more sources
Exact Minimax Optimality of Spectral Methods in Phase Synchronization and Orthogonal Group Synchronization [PDF]
We study the performance of the spectral method for the phase synchronization problem with additive Gaussian noises and incomplete data. The spectral method utilizes the leading eigenvector of the data matrix followed by a normalization step.
An Zhang
semanticscholar +1 more source
Groups whose Proper Subgroups of Infinite Rank are Minimax-by-Nilpotent or Nilpotent-by-Minimax [PDF]
Let M denote the class of of soluble-by-finite minimax groups, and N the class of nilpotent groups. The main result states that if G is a group of infinite rank whose proper subgroups of infinite rank are MN-groups, then G is either in MN or it is a ...
Amel Zitouni
doaj +1 more source
Design of Sparse FIR Filters with Low Group Delay [PDF]
The aim of the work is to present the method for designing sparse FIR filters with very low group delay and approximately linear-phase in the passband. Significant reduction of the group delay, e.g.
Jacek Konopacki
doaj +1 more source
Minimax Group Fairness: Algorithms and Experiments
We consider a recently introduced framework in which fairness is measured by worst-case outcomes across groups, rather than by the more standard differences between group outcomes.
Emily Diana +4 more
semanticscholar +1 more source
Fairness-aware Federated Minimax Optimization with Convergence Guarantee [PDF]
Federated learning (FL) has garnered considerable attention due to its privacy-preserving feature. Nonetheless, the lack of freedom in managing user data can lead to group fairness issues, where models are biased towards sensitive factors such as race or
Gerry Windiarto Mohamad Dunda +1 more
semanticscholar +1 more source
Groups with Finitely Many Isomorphism Classes of Non-Normal Subgroups [PDF]
We study groups in which the non-normal subgroups fall into finitely many isomorphism classes. We prove that a locally generalized radical group with this property is abelian-by-finite and minimax.
Leonid A. Kurdachenko +2 more
doaj +1 more source
GAN‐LSTM‐3D: An efficient method for lung tumour 3D reconstruction enhanced by attention‐based LSTM
Abstract Three‐dimensional (3D) image reconstruction of tumours can visualise their structures with precision and high resolution. In this article, GAN‐LSTM‐3D method is proposed for 3D reconstruction of lung cancer tumours from 2D CT images. Our method consists of three phases: lung segmentation, tumour segmentation, and tumour 3D reconstruction. Lung
Lu Hong +12 more
wiley +1 more source
Some remarks about groups of finite special rank [PDF]
The paper presents some results about groups of finite special and section ranks. For instance, among others, it was proved that if every locally (soluble minimax) subgroup of a generalized radical group G has finite special rank, then G has finite ...
L.A. Kurdachenko +2 more
doaj +1 more source

