Results 51 to 60 of about 13,046,168 (188)
Introduction Limited clinical studies have been conducted on rare solid tumours, and there are few guidelines on the diagnosis and treatment, including experiences with targeted therapy and immunotherapy, of rare solid tumours in China, resulting in ...
Hui Wang +22 more
doaj +1 more source
Summary: Background: Central nervous system (CNS) metastases is inevitable for epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC). AZD3759 is a novel EGFR-TKI with impressive CNS penetration.
Si-Yang Maggie Liu +25 more
doaj +1 more source
Sion's mini-max theorem and Nash equilibrium in a multi-players game with two groups which is zero-sum and symmetric in each group [PDF]
We consider the relation between Sion's minimax theorem for a continuous function and a Nash equilibrium in a multi-players game with two groups which is zero-sum and symmetric in each group. We will show the following results. 1. The existence of Nash
Satoh, Atsuhiro, Tanaka, Yasuhito
core +2 more sources
A unified minimax result for restricted parameter spaces
We provide a development that unifies, simplifies and extends considerably a number of minimax results in the restricted parameter space literature. Various applications follow, such as that of estimating location or scale parameters under a lower (or ...
Marchand, Éric, Strawderman, William E.
core +1 more source
Objective Immunothrombosis contributes to ischemic stroke pathophysiology through neutrophil extracellular trap (NET) formation, which promotes thrombus stabilization and microvascular dysfunction. DNase1 is the principal endonuclease responsible for NET degradation.
B. Díaz‐Benito +10 more
wiley +1 more source
Sequential Minimax Search for Multi-Layer Gene Grouping
Many areas of exploratory data analysis need to deal with high-dimensional data sets. Some real life data like human gene have an inherent structure of hierarchy, which embeds multi-layer feature groups.
Wenting Wang +3 more
doaj +1 more source
Background The standard lasso penalty and its extensions are commonly used to develop a regularized regression model while selecting candidate predictor variables on a time-to-event outcome in high-dimensional data. However, these selection methods focus
Shaima Belhechmi +3 more
doaj +1 more source
Background The research of biomarker-treatment interactions is commonly investigated in randomized clinical trials (RCT) for improving medicine precision. The hierarchical interaction constraint states that an interaction should only be in a model if its
Shaima Belhechmi +4 more
doaj +1 more source
Mellin Representation for the Heavy Flavor Contributions to Deep Inelastic Structure Functions [PDF]
We derive semi--analytic expressions for the analytic continuation of the Mellin transforms of the heavy flavor QCD coefficient functions for neutral current deep inelastic scattering in leading and next-to-leading order to complex values of the Mellin ...
Abbott +69 more
core +2 more sources
Search versus Knowledge: An Empirical Study of Minimax on KRK [PDF]
This article presents the results of an empirical experiment designed to gain insight into what is the effect of the minimax algorithm on the evaluation function. The experiment’s simulations were performed upon the KRK chess endgame.
Bratko, Ivan +2 more
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