Results 131 to 140 of about 5,740,582 (295)
Annals of Pure and Applied Logic, 1993 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
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Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
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An Approximation of Fuzzy Numbers Based on Polynomial Form Fuzzy Numbers
International Journal of Analysis and Applications, 2018 In this paper, we approximate an arbitrary fuzzy number by a polynomial fuzzy number through minimizing the distance between them. Throughout this work, we used a distance that is a meter on the set of all fuzzy numbers with continuous left and right ...
Sh. Yeganehmanesh, M. Amirfakhrian
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Area-minimizing Hypersurfaces in Singular Ambient Manifolds [PDF]
We study area-minimizing hypersurfaces in singular ambient manifolds whose tangent cones have nonnegative scalar curvature on their regular parts. We prove that the singular set of the hypersurface has codimension at least 3 in our settings. We also give
Wang, Yihan
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Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
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Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
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Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
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Uniqueness of area minimizing surfaces for extreme curves
, 2016 Let MM be a compact, orientable, mean convex 33-manifold with boundary ?M?M. We show that the set of all simple closed curves in ?M?M which bound unique area minimizing disks in MM is dense in the space of simple closed curves in ?M?M which are ...
Coşkunüzer, Barış; Etgü, Tolga
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