Results 71 to 80 of about 5,740,582 (295)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Riemannian Optimal Model Reduction of Stable Linear Systems
IEEE Access, 2019 In this paper, we develop a method for solving the problem of minimizing the H2 error norm between the transfer functions of the original and reduced systems on the product set of the set of stable matrices and two Euclidean spaces. That is, we develop a
Kazuhiro Sato
doaj +1 more source
An algorithm for computing the distance to uncontrollability [PDF]
, 1991 Elsner L, He C. An algorithm for computing the distance to uncontrollability. Systems & Control Letters. 1991;17(6):453-464.In this paper, we present an algorithm to compute the distance to uncontrollability.
He, Chunyang +3 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Keystroke features recognition based on stable linear discriminant analysis
Tongxin xuebao, 2017 A novel keystroke features recognition method based on stable linear discriminant Analysis (SLDA) was put forward.First of all,it maximum the dispersion between different sequences,while minimizing the dispersion between the same sequence set,maintain ...
Wei-guo SHEN, Wei WANG
doaj +2 more sources
Codes and Automata in Minimal Sets [PDF]
, 2015 We explore several notions concerning codes and automata in a restricted set of words S. We define a notion of S-degree of an automaton and prove an inequality relating the cardinality of a prefix code included in a minimal set S and its S-degree.
openaire +2 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
A Multi-objective Simulated Annealing for Simultaneous Two-Sided Assembly Line Balancing and Operators Assignment [PDF]
مدیریت تولید و عملیات, 2017 This paper presents a multi-objective simulated annealing algorithm for mixed-model two-sided assembly line balancing with multi skilled operators. The objectives of the proposed model are minimizing the number of mated-stations, the number of total ...
Parviz Fattahi +2 more
doaj
On Minimal and Minimum Hull Sets
Electronic Notes in Discrete Mathematics, 2013 Abstract A graph convexity ( G , C ) is a graph G together with a collection C of subsets of V ( G ) , called convex sets, such that ∅ , V ( G ) ∈ C and C is closed under intersections. For a set U ⊆ V ( G ) , the hull of U, denoted H ( U ) , is the smallest convex set containing U. If H
Rommel M. Barbosa +3 more
openaire +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source